Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 8/20 | 0.58 |
| ▸ | CA1 | P00915 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.58 |
| ▸ | CA4 | P22748 | 1/20 | 0.58 |
| ▸ | CA6 | P23280 | 1/20 | 0.58 |
| ▸ | CA5A | P35218 | 1/20 | 0.58 |
| ▸ | CA7 | P43166 | 1/20 | 0.58 |
| ▸ | CA9 | Q16790 | 1/20 | 0.58 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.58 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2248882 | 0.84 | CA1 (0.55) | CA2CA1CA12CA4CA6 | |
| SCHEMBL8337020 | 0.82 | CA2 (0.60) | CA2ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL5647044 | 0.81 | ALDH1A1 (0.50) | CA2ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL2861660 | 0.81 | CA2 (0.60) | CA2CA1CA12CA4CA6 | |
| SCHEMBL19249688 | 0.80 | ALDH1A1 (0.52) | CA2CA1ALDH1A1LMNAHTT | |
| Hydrochloric Acid SCHEMBL20497339 | 0.79 | F2 (0.59) | CA2CA1CA12CA4CA6 | |
| SCHEMBL18381561 | 0.78 | LMNA (0.47) | CA2ALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL17085975 | 0.78 | CA2 (0.47) | CA2CA1CA12CA4CA6 | |
| SCHEMBL1434498 | 0.78 | CA2 (0.64) | CA2CA1CA12CA4CA6 | |
| SCHEMBL4482607 | 0.78 | LMNA (0.60) | CA2ALDH1A1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |