Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.46 |
| ▸ | MARK3 | P27448 | 1/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.46 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.46 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.46 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28558504 | 0.79 | L3MBTL1 (0.57) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL20562433 | 0.78 | L3MBTL1 (0.49) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL5871186 | 0.77 | L3MBTL1 (0.51) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL29236564 | 0.76 | L3MBTL1 (0.57) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL25244266 | 0.74 | HTR6 (0.46) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL28247794 | 0.74 | L3MBTL1 (0.55) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL30620463 | 0.74 | L3MBTL1 (0.50) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL27257521 | 0.74 | L3MBTL1 (0.53) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL20561898 | 0.74 | L3MBTL1 (0.47) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL22969240 | 0.74 | BRD4 (0.49) | L3MBTL1BRD4CREBBPPIM1MARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |