Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 2/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.49 |
| ▸ | MARK3 | P27448 | 1/20 | 0.49 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.49 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.49 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.49 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30620463 | 0.82 | L3MBTL1 (0.50) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL23496956 | 0.82 | L3MBTL1 (0.53) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL30719630 | 0.82 | L3MBTL1 (0.53) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL5871186 | 0.81 | L3MBTL1 (0.51) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL31070592 | 0.79 | L3MBTL1 (0.47) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL29831138 | 0.79 | L3MBTL1 (0.47) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL23330849 | 0.79 | L3MBTL1 (0.47) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL121876 | 0.78 | SCN9A (0.43) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL22468928 | 0.78 | KMT2A (0.49) | L3MBTL1BRD4CREBBPPIM1MARK3 | |
| SCHEMBL24721683 | 0.78 | L3MBTL1 (0.46) | L3MBTL1BRD4CREBBPPIM1MARK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1024797-C | Indole derivatives | OTSUKA CHEMICAL CO LTD (JP) | 1994-06-01 | — | — | CN | disclosed |
| CN-1049155-A | INDOLE DERIVATIVES | OTSUKA CHEMICAL CO LTD (JP) | 1991-02-13 | — | — | CN | disclosed |