Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8102532 | 0.81 | ALDH1A1 (0.54) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL624054 | 0.73 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL7684242 | 0.73 | ALDH1A1 (0.64) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL28254105 | 0.73 | ALDH1A1 (0.72) | ALDH1A1MAPTKMT2ANPSR1PKM | |
| SCHEMBL29923915 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL12788041 | 0.72 | ALDH1A1 (1.00) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL14992158 | 0.72 | EPAS1 (0.47) | ALDH1A1MAPTLMNAKDM4ECRHBP | |
| SCHEMBL7673660 | 0.72 | ALDH1A1 (0.62) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL948375 | 0.72 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNAMEN1KMT2A | |
| SCHEMBL11577833 | 0.72 | ALDH1A1 (0.50) | ALDH1A1MAPTLMNAKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |