Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.60 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 1/20 | 0.46 |
| ▸ | HTR1F | P30939 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5353003 | 0.75 | HTR6 (1.00) | HTR6CYP3A4CYP2D6HTR1ADRD2 | |
| SCHEMBL7259899 | 0.75 | HTR6 (0.62) | HTR6CYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL26912016 | 0.74 | HTR6 (0.61) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL7974071 | 0.73 | HTR6 (0.62) | HTR6CYP3A4CYP2D6DRD2 | |
| SCHEMBL5349268 | 0.73 | HTR6 (0.78) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL7975063 | 0.73 | HTR6 (0.61) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5356815 | 0.72 | HTR6 (0.77) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL29978076 | 0.72 | ALDH1A1 (0.49) | CYP3A4CYP2D6 | |
| SCHEMBL30797875 | 0.71 | HTR6 (0.59) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL1413320 | 0.71 | HTR6 (0.59) | HTR6CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |