Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 9/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.36 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | CLK1 | P49759 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7882932 | 0.78 | HTR2C (0.61) | FFAR1GPR84HTR2AHTR6HTR2C | |
| SCHEMBL23570163 | 0.77 | HTR2A (0.42) | HTR2AHTR1AHTR6HTR2CCCNE1 | |
| SCHEMBL6296691 | 0.75 | DRD2 (0.60) | HTR2AHTR1AHTR6HTR2CCCNE1 | |
| SCHEMBL7859774 | 0.75 | SLC6A4 (0.64) | HTR1AHTR6SLC6A4KDM4EALOX15 | |
| Ethylene SCHEMBL7481976 | 0.73 | DRD2 (0.57) | HTR2AHTR1AHTR6HTR2CCCNE1 | |
| SCHEMBL18951170 | 0.73 | PTGS2 (0.42) | — | |
| SCHEMBL6638540 | 0.72 | FFAR1 (0.38) | FFAR1GPR84HTR2AHTR1AHTR7 | |
| SCHEMBL1256596 | 0.72 | PTGS2 (0.47) | — | |
| SCHEMBL1255397 | 0.71 | PTGS2 (0.46) | — | |
| SCHEMBL18324716 | 0.71 | TDO2 (0.67) | HTR1AHTR6SLC6A4KDM4EALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127333-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |