Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31736542 | 1.00 | HTR2C (0.44) | HTR2CEPHX2ALDH1A1KDM4E | |
| SCHEMBL4060441 | 0.85 | HTR2C (0.43) | HTR2CEPHX2ALDH1A1KDM4E | |
| SCHEMBL5466087 | 0.79 | POLB (0.52) | ALDH1A1KDM4E | |
| SCHEMBL29563688 | 0.79 | CHIA (0.46) | ALDH1A1 | |
| SCHEMBL1760423 | 0.79 | ALDH1A1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL30855570 | 0.79 | POLB (0.52) | ALDH1A1KDM4E | |
| SCHEMBL13116668 | 0.79 | HTR2C (0.56) | HTR2CEPHX2ALDH1A1KDM4E | |
| SCHEMBL4805575 | 0.79 | EPHX2 (0.40) | HTR2CEPHX2 | |
| SCHEMBL874422 | 0.78 | HRH1 (0.41) | HTR2CALDH1A1KDM4E | |
| SCHEMBL27686764 | 0.78 | ALDH1A1 (0.39) | HTR2CALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127443-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF ANDROGEN RECEPTOR | ARVINAS OPERATIONS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |