Oxytetracycline

Oxytetracycline

SCHEMBL2353677

CN(C)[C@@H]1C(O)=C(C(N)=O)C(=O)[C@@]2(O)C(O)=C3C(=O)c4c(O)cccc4[C@@](C)(O)[C@H]3[C@H](O)[C@@H]12.O.O.O.O

nearest known ligand 0.70

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Oxytetracycline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 9/20 0.70
MEN1 O00255 9/20 0.70
KMT2A Q03164 9/20 0.70
KDM4E B2RXH2 8/20 0.70
USP2 O75604 7/20 0.70
HPGD P15428 6/20 0.70
ALDH1A1 P00352 5/20 0.70
RECQL P46063 5/20 0.70
HSD17B10 Q99714 5/20 0.70
L3MBTL1 Q9Y468 4/20 0.70
HIF1A Q16665 3/20 0.70
LMNA P02545 3/20 0.70
ALOX15 P16050 2/20 0.70
CYP2C9 P11712 1/20 0.70
BRCA1 P38398 1/20 0.70
MAPT P10636 5/20 0.69
THRB P10828 4/20 0.69
POLB P06746 3/20 0.69
GAA P10253 1/20 0.69
MMP2 P08253 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Oxytetracycline SCHEMBL20740448 1.00 TDP1 (0.70) TDP1MEN1KMT2AKDM4EUSP2
Oxytetracycline SCHEMBL20740451 1.00 TDP1 (0.70) TDP1MEN1KMT2AKDM4EUSP2
Oxytetracycline SCHEMBL2898 1.00 TDP1 (0.70) TDP1MEN1KMT2AKDM4EUSP2
Oxytetracycline SCHEMBL22769463 0.99 TDP1 (0.69) TDP1MEN1KMT2AKDM4EUSP2
Oxytetracycline SCHEMBL11331676 0.99 TDP1 (0.69) TDP1MEN1KMT2AKDM4EUSP2
Oxytetracycline SCHEMBL21409869 0.99 TDP1 (0.69) TDP1MEN1KMT2AKDM4EUSP2
Oxytetracycline SCHEMBL3954956 0.99 TDP1 (0.69) TDP1MEN1KMT2AKDM4EUSP2
Oxytetracycline SCHEMBL10765981 0.99 TDP1 (0.69) TDP1MEN1KMT2AKDM4EUSP2
Oxytetracycline SCHEMBL459700 0.99 TDP1 (0.69) TDP1MEN1KMT2AKDM4EUSP2
Oxytetracycline SCHEMBL2806490 0.99 TDP1 (0.69) TDP1MEN1KMT2AKDM4EUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110693826-A Long-acting oxytetracycline injection for livestock and preparation method thereof 成都新亨药业有限公司 2020-01-17 CN claimed
EP-2351570-A1 An Antibiotic/Analgesic Formulation And a Method of Making This Formulation IVX Animal Health, Inc. (US) 2011-08-03 EP claimed
EP-1345611-A4 AN ANTIBIOTIC/ANALGESIC FORMULATION AND A METHOD OF MAKING THIS FORMULATION PHOENIX SCIENT INC (US) 2005-11-16 EP claimed
EP-1345611-A1 AN ANTIBIOTIC/ANALGESIC FORMULATION AND A METHOD OF MAKING THIS FORMULATION Phoenix Scientific, Inc. (US) 2003-09-24 EP claimed
WO-2002041899-A1 AN ANTIBIOTIC/ANALGESIC FORMULATION AND A METHOD OF MAKING THIS FORMULATION PHOENIX SCIENTIFIC, INC. (US) 2002-05-30 WO claimed
EP-0634995-B1 PROCESS AND INTERMEDIATE FOR THE PURIFICATION OF OXYTETRACYCLINE PLIVA HANDELS GMBH (DE) 1996-07-03 EP claimed
US-5387703-A Process and intermediate for the purification of oxytetracycline PLIVA (HR) 1995-02-07 US claimed
EP-0634995-A1 PROCESS AND INTERMEDIATE FOR THE PURIFICATION OF OXYTETRACYCLINE. PLIVA HANDELS GMBH (DE) 1995-01-25 EP claimed
WO-1993020042-A1 PROCESS AND INTERMEDIATE FOR THE PURIFICATION OF OXYTETRACYCLINE PLIVA HANDELS GMBH (DE) 1993-10-14 WO claimed
US-4772460-A INJECTING AQUEOUS SOLUTION CONTAINING N-METHYL PYRROLIDONE AND MAGNESIUM COMPOUND BIMEDA RESEARCH AND DEVELOPMENT, LTD. (IE) 1988-09-20 US claimed
EP-4727359-A1 FUNGICIDAL COMPOSITIONS Syngenta Crop Protection AG (CH) 2026-04-22 EP disclosed
WO-2026047037-A1 MICROBIOCIDAL QUINOLINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2026-03-05 WO disclosed
WO-2025233384-A1 MICROBIOCIDAL PYRAZOLE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2025-11-13 WO disclosed
WO-2025202482-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-10-02 WO disclosed
WO-2025202499-A1 FUNGICIDAL COMPOSITIONS SYNGENTA CROP PROTECTION AG (CH) 2025-10-02 WO disclosed
US-4772460-A INJECTING AQUEOUS SOLUTION CONTAINING N-METHYL PYRROLIDONE AND MAGNESIUM COMPOUND BIMEDA RESEARCH AND DEVELOPMENT, LTD. (IE) 1988-09-20 US disclosed
EP-0096942-B1 OXYTETRACYCLINE COMPOSITION AND PROCESS FOR PREPARING AN OXYTETRACYCLINE COMPOSITION Aesculaap B.V. (NL) 1986-03-19 EP disclosed
EP-0096942-A2 Oxytetracycline composition and process for preparing an oxytetracycline composition Aesculaap B.V. (NL) 1983-12-28 EP disclosed
US-4219545-A ADMINISTERING RIBOFLAVIN COLLINS CALVIN E 1980-08-26 US disclosed
US-3987797-A ANTIMICROBIAL SUTURES ETHICON, INC. (US) 1976-10-26 US disclosed