Tetrylammonium

Tetrylammonium

SCHEMBL2353698

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nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRB1ADRB2ATP4AATP4BAXLCHRM2CHRM3DRD2FLT3HRH1HTR2AHTR2BHTR2CKCNH2KMT2AMAP2K1MAP2K2MEN1MLNRPLK4RENS1PR1SLC6A2SLC6A4atpAatpBatpCatpDatpEatpFatpFHatpGpol

The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.53
TP53 P04637 1/20 0.53
EGLN1 Q9GZT9 1/20 0.53
EGLN3 Q9H6Z9 1/20 0.53
HCAR2 Q8TDS4 7/20 0.48
NFKB1 P19838 1/20 0.47
KCNA1 Q09470 1/20 0.47
KDM4E B2RXH2 1/20 0.44
PMP22 Q01453 1/20 0.44
ATM Q13315 1/20 0.44
GABRR1 P24046 2/20 0.38
GABRR2 P28476 2/20 0.38
BLM P54132 2/20 0.38
GABRR3 A8MPY1 1/20 0.38
LMNA P02545 1/20 0.38
APEX1 P27695 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.37
GAA P10253 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrylammonium SCHEMBL2349571 1.00 TSHR (0.53) TSHRTP53EGLN1EGLN3HCAR2
Tetrylammonium SCHEMBL9617210 1.00 TSHR (0.53) TSHRTP53EGLN1EGLN3HCAR2
Tetrylammonium SCHEMBL2351492 1.00 TSHR (0.53) TSHRTP53EGLN1EGLN3HCAR2
Tetrylammonium SCHEMBL2348763 1.00 TSHR (0.53) TSHRTP53EGLN1EGLN3HCAR2
Tetrylammonium SCHEMBL2351938 0.97 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
Tetrylammonium SCHEMBL2346203 0.97 TSHR (0.50) TSHRTP53EGLN1EGLN3HCAR2
Tetrylammonium SCHEMBL2349569 0.88 TSHR (0.41) TSHRTP53EGLN1EGLN3HCAR2
Tetrylammonium SCHEMBL2452720 0.88 TSHR (0.41) TSHRTP53EGLN1EGLN3HCAR2
Tetrylammonium SCHEMBL2351488 0.88 TSHR (0.41) TSHRTP53EGLN1EGLN3HCAR2
Tetrylammonium SCHEMBL6552606 0.87 TSHR (0.40) TSHRTP53EGLN1EGLN3HCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 56 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3481878-B1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-05-22 EP claimed
CN-109476803-B Amine compositions useful for making polyurethane foams 赢创运营有限公司 2022-04-12 CN claimed
US-11021561-B2 Amine composition useful for making polyurethane foam EVONIK OPERATIONS GMBH (DE) 2021-06-01 US claimed
EP-3144332-B1 NEW TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY EVONIK OPERATIONS GMBH (DE) 2020-10-21 EP claimed
EP-3481878-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM Evonik Degussa GmbH (DE) 2019-05-15 EP claimed
US-9878318-B2 Trimer catalyst additives for improving foam processability EVONIK DEGUSSA GMBH (DE) 2018-01-30 US claimed
WO-2018013590-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK DEGUSSA GMBH (DE) 2018-01-18 WO claimed
US-20180009930-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2018-01-11 US claimed
US-9815932-B2 Trimer catalysts with improved processability and surface cure EVONIK DEGUSSA GMBH (DE) 2017-11-14 US claimed
EP-1852450-B1 New trimer catalyst additives for improving foam processability AIR PROD & CHEM (US) 2016-12-14 EP claimed
US-20140042361-A1 TRIMER CATALYSTS WITH IMPROVED PROCESSABILITY AND SURFACE CURE EVONIK OPERATIONS GMBH (DE) 2014-02-13 US claimed
US-20140005037-A1 TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY EVONIK OPERATIONS GMBH (DE) 2014-01-02 US claimed
US-8580864-B2 Trimer catalysts with improved processability and surface cure AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-11-12 US claimed
US-8552077-B2 Trimer catalyst additives for improving foam processability AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-10-08 US claimed
EP-2003157-A2 Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications Air Products and Chemicals, Inc. (US) 2008-12-17 EP claimed
US-20070259982-A1 Trimer catalysts with improved processability and surface cure EVONIK OPERATIONS GMBH (DE) 2007-11-08 US claimed
US-20070259773-A1 Trimer catalyst additives for improving foam processability EVONIK OPERATIONS GMBH (DE) 2007-11-08 US claimed
EP-1852449-A2 New trimer catalyst with improved processability and surface cure Air Products and Chemicals, Inc. (US) 2007-11-07 EP claimed
EP-1852450-A2 New trimer catalyst additives for improving foam processability Air Products and Chemicals, Inc. (US) 2007-11-07 EP claimed
US-20260044081-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2026-02-12 US disclosed
EP-4692941-A2 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2026-02-11 EP disclosed
EP-3481878-B1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2024-05-22 EP disclosed
CN-114660896-A Composition for forming silicon-containing resist underlayer film, pattern forming method, and silicon compound 信越化学工业株式会社 2022-06-24 CN disclosed
CN-109476803-B Amine compositions useful for making polyurethane foams 赢创运营有限公司 2022-04-12 CN disclosed
CN-107922564-B Trimerization catalysts from sterically hindered salts and tertiary amines having isocyanate-reactive groups 赢创运营有限公司 2021-10-19 CN disclosed
US-11021561-B2 Amine composition useful for making polyurethane foam EVONIK OPERATIONS GMBH (DE) 2021-06-01 US disclosed
EP-3310827-B1 TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS EVONIK OPERATIONS GMBH (DE) 2021-01-06 EP disclosed
CN-111855581-A Method for determining diffusion distance of hardening catalyst 信越化学工业株式会社 2020-10-30 CN disclosed
EP-3144332-B1 NEW TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY EVONIK OPERATIONS GMBH (DE) 2020-10-21 EP disclosed
US-10759892-B2 Trimerization catalysts from sterically hindered salts and tertiary amines having isocyanate reactive groups EVONIK OPERATIONS GMBH (DE) 2020-09-01 US disclosed
US-20180179318-A1 TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS EVONIK OPERATIONS GMBH (DE) 2018-06-28 US disclosed
EP-3310827-A1 TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS Evonik Degussa GmbH (DE) 2018-04-25 EP disclosed
US-9890236-B2 Trimerization catalysts from sterically hindered salts EVONIK DEGUSSA GMBH (DE) 2018-02-13 US disclosed
US-9878318-B2 Trimer catalyst additives for improving foam processability EVONIK DEGUSSA GMBH (DE) 2018-01-30 US disclosed
US-20180009930-A1 AMINE COMPOSITION USEFUL FOR MAKING POLYURETHANE FOAM EVONIK OPERATIONS GMBH (DE) 2018-01-11 US disclosed
US-9815932-B2 Trimer catalysts with improved processability and surface cure EVONIK DEGUSSA GMBH (DE) 2017-11-14 US disclosed
EP-3144332-A1 NEW TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY AIR PRODUCTS AND CHEMICALS, INC. (US) 2017-03-22 EP disclosed
WO-2016201675-A1 TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AND TERTIARY AMINES HAVING ISOCYANATE REACTIVE GROUPS AIR PRODUCTS AND CHEMICALS, INC. (US) 2016-12-22 WO disclosed
EP-1852450-B1 New trimer catalyst additives for improving foam processability AIR PROD & CHEM (US) 2016-12-14 EP disclosed
US-20140042361-A1 TRIMER CATALYSTS WITH IMPROVED PROCESSABILITY AND SURFACE CURE EVONIK OPERATIONS GMBH (DE) 2014-02-13 US disclosed
US-20140005037-A1 TRIMER CATALYST ADDITIVES FOR IMPROVING FOAM PROCESSABILITY EVONIK OPERATIONS GMBH (DE) 2014-01-02 US disclosed
US-20130341562-A1 TRIMERIZATION CATALYSTS FROM STERICALLY HINDERED SALTS AIR PRODUCTS AND CHEMICALS INC. (US) 2013-12-26 US disclosed
US-8580864-B2 Trimer catalysts with improved processability and surface cure AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-11-12 US disclosed
US-8552077-B2 Trimer catalyst additives for improving foam processability AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-10-08 US disclosed
US-8530534-B2 Trimerization catalysts from sterically hindered salts AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-09-10 US disclosed
EP-1852448-B1 New trimerization catalysts from sterically hindered salts AIR PROD & CHEM (US) 2011-08-31 EP disclosed
EP-2003157-A2 Tetraalkylammonium carboxylate salts as trimerization catalysts for spray foam applications Air Products and Chemicals, Inc. (US) 2008-12-17 EP disclosed
US-20070259982-A1 Trimer catalysts with improved processability and surface cure EVONIK OPERATIONS GMBH (DE) 2007-11-08 US disclosed
US-20070259773-A1 Trimer catalyst additives for improving foam processability EVONIK OPERATIONS GMBH (DE) 2007-11-08 US disclosed
US-20070259983-A1 Trimerization catalysts from sterically hindered salts EVONIK OPERATIONS GMBH (DE) 2007-11-08 US disclosed
EP-1852449-A2 New trimer catalyst with improved processability and surface cure Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed
EP-1852450-A2 New trimer catalyst additives for improving foam processability Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed
EP-1852448-A2 New trimerization catalysts from sterically hindered salts Air Products and Chemicals, Inc. (US) 2007-11-07 EP disclosed
EP-1048457-B1 Lithographic printing plate precursor FUJI PHOTO FILM CO LTD (JP) 2004-12-15 EP disclosed
US-6455224-B1 SUPPORT WITH HYDROPHILIC SURFACE AND PHOTOSENSITIVE LAYER CONTAINING INFRARED ABSORBENT WHICH CHANGES FROM HYDROPHILIC TO HYDROPHOBIC BY HEAT AND HYDROPHILIC POLYMER HAVING FUNCTIONAL GROUP RENDERING LAYER WATER DEVELOPABLE FUJI PHOTO FILM CO., LTD. (JP) 2002-09-24 US disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed
EP-1048457-A2 Lithographic printing plate precursor FUJI PHOTO FILM CO., LTD. (JP) 2000-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260044081-A1 COMPOSITION FOR FORMING SILICON-CONTAINING RESIST FILM AND PATTERNING PROCESS SMC1A, SPOUT1, LBR TSHR 446/4885TP53 4717/4885EGLN1 1989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.