Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23538144 | 0.79 | MAPT (0.63) | L3MBTL1KDM4EMAPTALDH1A1LMNA | |
| SCHEMBL23537751 | 0.79 | HPGD (0.49) | L3MBTL1KDM4EMAPTALDH1A1MRGPRX4 | |
| SCHEMBL23538009 | 0.79 | HPGD (0.40) | L3MBTL1KDM4EMAPTALDH1A1MRGPRX4 | |
| SCHEMBL23538003 | 0.76 | NPC1 (0.39) | L3MBTL1MAPTALDH1A1MRGPRX4LMNA | |
| SCHEMBL23538138 | 0.76 | L3MBTL1 (0.48) | L3MBTL1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL30729931 | 0.75 | HTR2A (0.52) | KDM4EMAPTALDH1A1MRGPRX4MEN1 | |
| SCHEMBL27096948 | 0.75 | HTR2A (0.52) | KDM4EMAPTALDH1A1MRGPRX4MEN1 | |
| SCHEMBL23538130 | 0.74 | SYK (0.45) | ALDH1A1MRGPRX4SYKCYP3A4CYP1A2 | |
| SCHEMBL15304829 | 0.74 | MRGPRX4 (0.44) | MAPTALDH1A1MRGPRX4MEN1KMT2A | |
| SCHEMBL8308433 | 0.74 | TDP1 (0.44) | L3MBTL1MAPTMRGPRX4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127397-A1 | NITROGEN HETEROCYCLIC COMPOUNDS AND METHODS OF USE | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |