SCHEMBL23539

SCHEMBL23539

Cc1ccc(-c2nc(-c3ccccc3)nc3c2ccc2c(-c4ccccc4)cc(-c4ccccc4)nc23)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.48
KDM4E B2RXH2 7/20 0.46
MEN1 O00255 7/20 0.46
KMT2A Q03164 7/20 0.46
HPGD P15428 5/20 0.46
MAPT P10636 5/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
NPSR1 Q6W5P4 3/20 0.45
LMNA P02545 2/20 0.45
DPP4 P27487 1/20 0.45
RECQL P46063 1/20 0.45
ADORA2A P29274 2/20 0.43
ADORA1 P30542 2/20 0.43
PPARG P37231 2/20 0.43
NCOA2 Q15596 1/20 0.43
NCOA1 Q15788 1/20 0.43
NCOA3 Q9Y6Q9 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
AGTR1 P30556 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10000975 0.92 MEN1 (0.45) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL595855 0.92 ADORA2A (0.45) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL25850701 0.90 ALDH1A1 (0.40) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL14560694 0.87 KDM4E (0.57) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL13458726 0.87 KDM4E (0.57) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL29455177 0.87 KDM4E (0.57) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL347336 0.86 ADORA1 (0.42) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL3697872 0.86 KDM4E (0.56) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL13458698 0.86 KDM4E (0.56) ALDH1A1KDM4EMEN1KMT2AHPGD
SCHEMBL3699265 0.86 KDM4E (0.56) ALDH1A1KDM4EMEN1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2789027-B1 ORGANIC PHOTOVOLTAIC DEVICE NOVALED GMBH (DE) 2019-08-14 EP disclosed
EP-2789028-B1 ORGANIC LIGHT EMITTING DEVICE AND METHOD OF PRODUCING NOVALED GMBH (DE) 2019-02-06 EP disclosed
US-9318705-B2 Organic light emitting device with roughening layer and method of producing NOVALED GMBH (DE) 2016-04-19 US disclosed
US-9178173-B2 Organic light emitting device NOVALED AG (DE) 2015-11-03 US disclosed
US-20140332794-A1 Organic Light Emitting Device and Method of Producing NOVALED GMBH (DE) 2014-11-13 US disclosed
US-20140326310-A1 Organic Photovoltaic Device NOVALED GMBH (DE) 2014-11-06 US disclosed
EP-2789028-A1 ORGANIC LIGHT EMITTING DEVICE AND METHOD OF PRODUCING Novaled GmbH (DE) 2014-10-15 EP disclosed
US-20130320307-A1 Organic Light Emitting Device NOVALED AG (DE) 2013-12-05 US disclosed
WO-2013083712-A1 ORGANIC LIGHT EMITTING DEVICE AND METHOD OF PRODUCING NOVALED AG (DE) 2013-06-13 WO disclosed
US-8329898-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2012-12-11 US disclosed
US-20120041197-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These NOVALED AG (DE) 2012-02-16 US disclosed
US-8115003-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2012-02-14 US disclosed
WO-2011157385-A2 ORGANIC LIGHT EMITTING DEVICE NOVALED AG (DE) 2011-12-22 WO disclosed
US-20110046374-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These NOVALED AG (DE) 2011-02-24 US disclosed
US-7807687-B2 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2010-10-05 US disclosed
EP-1970371-B1 Pyrido(3,2-h)chinazolins and/or 5,6-Dihydro derivatives thereof, method for their manufacture and endowed organic semiconductor material containing them NOVALED AG (DE) 2010-08-25 EP disclosed
US-20080227979-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these NOVALED AG (DE) 2008-09-18 US disclosed
EP-1970371-A1 Pyrido(3,2-h)chinazolins and/or 5,6-Dihydro derivatives thereof, method for their manufacture and endowed organic semiconductor material containing them Novaled AG (DE) 2008-09-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120041197-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These PDXK, PNPO, QDPR ALDH1A1 1907/4885KDM4E 1296/4885MEN1 2966/4885
US-20080227979-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro derivatives thereof, a method for the production thereof and doped organic semiconductor material containing these PDXK, PNPO, QDPR ALDH1A1 1907/4885KDM4E 1296/4885MEN1 2966/4885
US-20110046374-A1 Pyrido[3,2-h]quinazolines and/or 5,6-dihydro Derivatives Thereof, a Method for the Production Thereof and Doped Organic Semiconductor Material Containing These PDXK, PNPO, QDPR ALDH1A1 1907/4885KDM4E 1296/4885MEN1 2966/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.