Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | PMM2 | O15305 | 1/20 | 0.37 |
| ▸ | MPI | P34949 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24900283 | 0.90 | KDM4E (0.44) | MAPTTP53HPGDLMNAGAA | |
| SCHEMBL21913084 | 0.86 | KDM4E (0.50) | MAPTHPGDLMNAGAASMN1; SMN2 | |
| SCHEMBL21416133 | 0.86 | KDM4E (0.50) | MAPTHPGDLMNAGAASMN1; SMN2 | |
| SCHEMBL21446374 | 0.84 | HPGD (0.40) | MAPTTP53ALDH1A1HPGDLMNA | |
| SCHEMBL22672123 | 0.84 | MAPT (0.38) | MAPTTP53ALDH1A1HPGDLMNA | |
| SCHEMBL21913931 | 0.82 | SMN1; SMN2 (0.41) | MAPTTP53ALDH1A1HPGDLMNA | |
| SCHEMBL22665063 | 0.79 | USP14 (0.36) | ALDH1A1HPGDNOTUM | |
| SCHEMBL21446670 | 0.79 | GAA (0.43) | MAPTTP53ALDH1A1HPGDLMNA | |
| SCHEMBL22294724 | 0.78 | KDM4E (0.44) | MAPTGAAMEN1KMT2AUSP2 | |
| SCHEMBL25806568 | 0.78 | LPL (0.34) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342774-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING ELEMENT COMPRISING SAME | LG CHEMICAL LTD (KR) | 2021-06-23 | — | — | EP | disclosed |