Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.47 |
| ▸ | CASP2 | P42575 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.39 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.39 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.39 |
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22423516 | 0.82 | GLP1R (0.54) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL26803766 | 0.78 | GLP1R (0.57) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL19057810 | 0.78 | GLP1R (0.57) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL21572002 | 0.77 | GLP1R (0.54) | GLP1RCASP2FAAHNAAADNM1 | |
| SCHEMBL29302105 | 0.76 | CASP2 (0.54) | GLP1RCASP2FAAHNAAAL3MBTL1 | |
| SCHEMBL7647954 | 0.75 | FAAH (0.62) | GLP1RCASP2FAAHENPP2LPAR1 | |
| SCHEMBL13811075 | 0.75 | FAAH (0.62) | GLP1RCASP2FAAHENPP2LPAR1 | |
| SCHEMBL7650140 | 0.75 | FAAH (0.62) | GLP1RCASP2FAAHENPP2LPAR1 | |
| SCHEMBL7646590 | 0.75 | FAAH (0.62) | GLP1RCASP2FAAHENPP2LPAR1 | |
| SCHEMBL20272601 | 0.75 | GLP1R (0.58) | GLP1RCASP2FAAHLPAR1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3447067-B1 | GLP-1R/GCGR DUAL TARGET AGONIST POLYPEPTIDE FOR TREATING NON-ALCOHOLIC FATTY LIVER DISEASES | SHENZHEN TURIER BIOTECH CO LTD (CN) | 2021-06-23 | — | — | EP | disclosed |