Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.54 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.43 |
| ▸ | CASP2 | P42575 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 3/20 | 0.42 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23544192 | 0.92 | GLP1R (0.53) | GLP1RDNM1CASP2FAAHNOD1 | |
| SCHEMBL22423517 | 0.91 | GLP1R (0.49) | GLP1REPHX2 | |
| SCHEMBL21389121 | 0.89 | CASP2 (0.53) | GLP1RDNM1CASP2FAAHNOD1 | |
| SCHEMBL23544191 | 0.88 | GLP1R (0.55) | GLP1RDNM1CASP2FAAHNOD1 | |
| SCHEMBL23552373 | 0.85 | GLP1R (0.51) | GLP1RCASP2FAAHNOD1 | |
| SCHEMBL21572003 | 0.82 | GLP1R (0.70) | GLP1RNOD1EPHX2 | |
| SCHEMBL22478893 | 0.82 | GLP1R (0.68) | GLP1RCASP2FAAHNOD1NAAA | |
| SCHEMBL23544184 | 0.82 | GLP1R (0.47) | GLP1RDNM1CASP2FAAHNAAA | |
| SCHEMBL23544185 | 0.82 | GLP1R (0.69) | GLP1RNOD1EPHX2 | |
| SCHEMBL26803766 | 0.81 | GLP1R (0.57) | GLP1RDNM1CASP2FAAHNOD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3708577-A1 | TREATMENT OF BILIARY CIRRHOSIS BASED ON OXYNTOMODULIN ANALOGUE GLP-1R/GCGR DUAL-TARGET AGONIST PEPTIDE | Shenzhen Turier Biotech Co., Ltd. (CN) | 2020-09-16 | — | — | EP | disclosed |