Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.39 |
| ▸ | ITGAV | P06756 | 3/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CDC25B | P30305 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HRH4 | Q9H3N8 | 4/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18936088 | 0.87 | LMNA (0.48) | LMNAITGB3ITGAVPTPN1ALDH1A1 | |
| SCHEMBL18935979 | 0.81 | ALDH1A1 (0.60) | LMNAPTPN1ALDH1A1CDC25BPOLB | |
| SCHEMBL18935956 | 0.77 | LMNA (0.45) | LMNAPTPN1CDC25BDRD1TAAR1 | |
| SCHEMBL17490859 | 0.77 | LMNA (0.46) | LMNAITGB3ITGAVITGA2BMEN1 | |
| SCHEMBL19194192 | 0.75 | LMNA (0.43) | LMNAPTPN1ALDH1A1CDC25BDRD1 | |
| SCHEMBL17490749 | 0.75 | HDAC3 (0.45) | LMNAITGB3ITGAVITGA2BMEN1 | |
| SCHEMBL18936020 | 0.75 | LMNA (0.42) | LMNAALDH1A1NPC1RAB9ACYP1A2 | |
| SCHEMBL17490892 | 0.74 | LMNA (0.46) | LMNAALDH1A1NPC1USP2ESR1 | |
| SCHEMBL17490911 | 0.74 | HDAC3 (0.47) | LMNAITGB3ITGAVITGA2B | |
| SCHEMBL19194711 | 0.73 | HDAC3 (0.43) | LMNAITGB3ITGAVALDH1A1ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3178323-B1 | NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2021-06-23 | — | — | EP | disclosed |