SCHEMBL18935979

SCHEMBL18935979

CCOC(=O)C1=NOC(COCc2ccccc2)C1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.60
L3MBTL1 Q9Y468 1/20 0.51
HTT P42858 1/20 0.45
CYP2C19 P33261 2/20 0.44
POLB P06746 1/20 0.44
CYP3A4 P08684 1/20 0.44
PTPN1 P18031 2/20 0.42
CDC25B P30305 1/20 0.42
TACR2 P21452 2/20 0.42
LMNA P02545 2/20 0.41
GAA P10253 2/20 0.40
MAPT P10636 2/20 0.40
CSNK1D P48730 1/20 0.40
KMT2A Q03164 2/20 0.40
MEN1 O00255 1/20 0.40
CYP1A2 P05177 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
MIF P14174 1/20 0.40
ACHE P22303 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18935966 0.89 ALDH1A1 (0.48) ALDH1A1L3MBTL1HTTCYP2C19POLB
SCHEMBL18936036 0.88 ALDH1A1 (0.53) ALDH1A1L3MBTL1HTTCYP2C19POLB
SCHEMBL18936009 0.88 ALDH1A1 (0.58) ALDH1A1L3MBTL1HTTCYP2C19POLB
SCHEMBL19181425 0.87 ALDH1A1 (0.54) ALDH1A1L3MBTL1HTTCYP2C19POLB
SCHEMBL18935977 0.86 ALDH1A1 (0.51) ALDH1A1L3MBTL1HTTCYP2C19POLB
SCHEMBL18936040 0.85 ALDH1A1 (0.50) ALDH1A1L3MBTL1HTTCYP2C19POLB
SCHEMBL892286 0.85 ALDH1A1 (0.58) ALDH1A1L3MBTL1HTTCYP2C19POLB
SCHEMBL18936088 0.85 LMNA (0.48) ALDH1A1POLBPTPN1CDC25BLMNA
SCHEMBL17490895 0.85 ALDH1A1 (0.49) ALDH1A1L3MBTL1HTTCYP2C19POLB
SCHEMBL18935994 0.85 ALDH1A1 (0.49) ALDH1A1L3MBTL1HTTCYP2C19POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3178323-B1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL CO (JP) 2021-06-23 EP disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 US disclosed
US-9854803-B2 Noxious arthropod control agent containing amide compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2018-01-02 US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 US disclosed
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-08-03 US disclosed
EP-3178323-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND Sumitomo Chemical Company, Limited (JP) 2017-06-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170215424-A1 NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND TRPA1, OPRM1, OPRL1 ALDH1A1 2079/4885L3MBTL1 12/4885HTT 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.