SCHEMBL2354604

SCHEMBL2354604

O=C(Oc1ccc(Cl)cc1)c1cc(O)c2ccccc2c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.53
MAPT P10636 6/20 0.51
MCL1 Q07820 4/20 0.51
KDM4E B2RXH2 3/20 0.51
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
NSD2 O96028 2/20 0.51
POLB P06746 1/20 0.51
TP53 P04637 2/20 0.47
ESR1 P03372 2/20 0.46
ESR2 Q92731 2/20 0.46
HPGD P15428 3/20 0.45
HSD17B10 Q99714 3/20 0.45
ALOX15 P16050 1/20 0.45
PTGS2 P35354 1/20 0.45
CYP1A2 P05177 1/20 0.43
CYP2C9 P11712 1/20 0.43
CYP2C19 P33261 1/20 0.43
ATM Q13315 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL590944 0.88 THRB (0.64) THRBMAPTMCL1KDM4EMEN1
SCHEMBL2296549 0.79 CYP1B1 (0.56) THRBMAPTKDM4EMEN1KMT2A
SCHEMBL2354417 0.79 ESR1 (0.59) THRBMAPTMCL1KDM4EMEN1
SCHEMBL7797719 0.79 MAPT (0.66) THRBMAPTKDM4EMEN1KMT2A
SCHEMBL10493714 0.78 MAPT (0.50) THRBMAPTKDM4EMEN1KMT2A
SCHEMBL6659667 0.78 HPGD (0.73) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL31557557 0.78 HPGD (0.73) MAPTKDM4EMEN1KMT2APOLB
SCHEMBL9394319 0.77 HPGD (0.55) THRBMAPTKDM4EMEN1KMT2A
SCHEMBL28785606 0.76 HPGD (0.53) THRBMAPTKDM4EMEN1KMT2A
SCHEMBL1791233 0.74 KDM4E (0.66) THRBMAPTMCL1KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8354359-B2 Heat-sensitive adhesive agent and heat-sensitive adhesive sheet RICOH COMPANY, LTD. (JP) 2013-01-15 US disclosed
EP-2062953-B1 Heat-sensitive adhesive material RICOH CO LTD (JP) 2011-08-17 EP disclosed
EP-2062953-A1 Heat-sensitive adhesive material Ricoh Company, Ltd. (JP) 2009-05-27 EP disclosed
US-20090130441-A1 HEAT-SENSITIVE ADHESIVE MATERIAL RICOH COMPANY, LTD (JP) 2009-05-21 US disclosed
US-20080176012-A1 Heat-sensitive adhesive agent and heat-sensitive adhesive sheet RICOH COMPANY, LTD. (JP) 2008-07-24 US disclosed
EP-1897925-A1 Heat-sensitive adhesive agent and heat-sensitive adhesive sheet Ricoh Company, Ltd. (JP) 2008-03-12 EP disclosed