SCHEMBL7797719

SCHEMBL7797719

O=C(Oc1ccccc1)c1cc(Cl)c2ccccc2c1O

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.66
KDM4E B2RXH2 5/20 0.66
HPGD P15428 3/20 0.66
HSD17B10 Q99714 3/20 0.66
ALDH1A1 P00352 3/20 0.66
MEN1 O00255 2/20 0.66
PKM P14618 2/20 0.66
KMT2A Q03164 2/20 0.66
HTT P42858 1/20 0.66
ALOX15 P16050 1/20 0.51
NSD2 O96028 1/20 0.49
TP53 P04637 2/20 0.48
NR4A2 P43354 1/20 0.48
LMNA P02545 1/20 0.48
CYP3A4 P08684 1/20 0.48
ADORA3 P0DMS8 1/20 0.48
CHRM1 P11229 1/20 0.48
TBXA2R P21731 1/20 0.48
SLC6A2 P23975 1/20 0.48
PDE4A P27815 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL590944 0.84 THRB (0.64) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL11066829 0.81 HPGD (0.51) MAPTKDM4EHPGDHSD17B10MEN1
SCHEMBL31300298 0.81 KDM4E (0.65) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL13401400 0.81 KDM4E (0.65) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL485443 0.80 HSD17B10 (1.00) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL28054156 0.79 STK39 (0.57) MAPTKDM4EHPGDHSD17B10KMT2A
SCHEMBL2354604 0.79 THRB (0.53) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL10997377 0.78 HPGD (0.55) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL5612390 0.78 MAPT (0.58) MAPTKDM4EHPGDHSD17B10ALDH1A1
SCHEMBL10489198 0.77 ALOX5 (0.50) MAPTKDM4EHPGDHSD17B10ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0718687-B1 Photographic element containing a novel cyan dye forming a coupler and process for its use EASTMAN KODAK CO (US) 2001-11-28 EP disclosed
EP-0718687-A1 Photographic element containing a novel cyan dye forming a coupler and process for its use EASTMAN KODAK COMPANY (US) 1996-06-26 EP disclosed
US-5476757-A Improved hue EASTMAN KODAK COMPANY (US) 1995-12-19 US disclosed
US-4454340-A Preparation of aryl 1-hydroxyaryl-2-carboxylates EASTMAN KODAK COMPANY (US) 1984-06-12 US disclosed