Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7790893 | 0.83 | — | — | |
| SCHEMBL4588754 | 0.82 | — | — | |
| Hydrochloric Acid SCHEMBL6908274 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL7792103 | 0.73 | PNMT (0.35) | — | |
| SCHEMBL4477976 | 0.68 | — | — | |
| Hydrochloric Acid SCHEMBL149639 | 0.66 | — | — | |
| Hydrochloric Acid SCHEMBL258210 | 0.66 | — | — | |
| Fluoride SCHEMBL1539635 | 0.66 | — | — | |
| Iodide SCHEMBL1539697 | 0.66 | — | — | |
| Bromide SCHEMBL1539587 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1448616-B1 | METHODS FOR ADJUSTING MELT PROPERTIES OF METALLOCENE CATALYZED OLEFIN COPOLYMERS | UNIVATION TECH LLC (US) | 2011-08-31 | — | — | EP | disclosed |
| US-6960634-B2 | Methods for adjusting melt properties of metallocene catalyzed olefin copolymers | UNIVATION TECHNOLOGIES, LLC (US) | 2005-11-01 | — | — | US | disclosed |
| EP-1448616-A2 | METHODS FOR ADJUSTING MELT PROPERTIES OF METALLOCENE CATALYZED OLEFIN COPOLYMERS | Univation Technologies LLC (US) | 2004-08-25 | — | — | EP | disclosed |
| US-20030105251-A1 | Methods for adjusting melt properties of metallocene catalyzed olefin copolymers | UNIVATION TECHNOLOGIES, LLC | 2003-06-05 | — | — | US | disclosed |
| WO-2003037938-A2 | METHODS FOR ADJUSTING MELT PROPERTIES OF METALLOCENE CATALYZED OLEFIN COPOLYMERS | UNIVATION TECHNOLOGIES, LLC (US) | 2003-05-08 | — | — | WO | disclosed |
| EP-1151019-A1 | GERMANIUM BRIDGED METALLOCENES PRODUCING POLYMERS WITH INCREASED MELT STRENGTH | Univation Technologies LLC (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000040622-A1 | GERMANIUM BRIDGED METALLOCENES PRODUCING POLYMERS WITH INCREASED MELT STRENGTH | UNIVATION TECHNOLOGIES, LLC (US) | 2000-07-13 | — | — | WO | disclosed |
| US-6034192-A | POLYMERIZING ETHYLENE USING COORDINATION CATALYST | UNIVATION TECHNOLOGIES, LLC (US) | 2000-03-07 | — | — | US | disclosed |