Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | LIMK1 | P53667 | 2/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | FYN | P06241 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23547231 | 0.85 | CYP2A6 (0.55) | KDM4EALDH1A1RAB9ASMN1; SMN2FYN | |
| SCHEMBL23547222 | 0.83 | MEN1 (0.43) | KDM4EALDH1A1LIMK1MAPK14MAPT | |
| SCHEMBL23535588 | 0.82 | LDHA (0.53) | KDM4EALDH1A1LIMK1MAPK14MAPT | |
| SCHEMBL28963414 | 0.82 | ALDH1A1 (0.45) | KDM4EALDH1A1LIMK1MAPK14MAPT | |
| SCHEMBL23535500 | 0.80 | MKNK1 (0.51) | KDM4EALDH1A1LIMK1MAPK14MAPT | |
| SCHEMBL23535509 | 0.80 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTALDH1A3MKNK1 | |
| SCHEMBL23547241 | 0.76 | MKNK1 (0.59) | ALDH1A1MKNK1MKNK2SMN1; SMN2TSHR | |
| SCHEMBL23547234 | 0.76 | KMT2A (0.45) | KDM4EALDH1A1LIMK1MAPK14MAPT | |
| SCHEMBL17055512 | 0.75 | MEN1 (0.55) | KDM4EALDH1A1MAPTTDP1SLC2A1 | |
| SCHEMBL23535481 | 0.75 | CACNA1B (0.52) | KDM4EALDH1A1MAPTTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021126923-A1 | CD206 MODULATORS THEIR USE AND METHODS FOR PREPARATION | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES (US) | 2021-06-24 | — | — | WO | disclosed |