Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK9 | P50750 | 17/20 | 0.45 |
| ▸ | CDK4 | P11802 | 2/20 | 0.45 |
| ▸ | CDK7 | P50613 | 2/20 | 0.45 |
| ▸ | CDK2 | P24941 | 16/20 | 0.45 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23547350 | 0.93 | CDK9 (0.50) | CDK9CDK4CDK7CDK2TLR9 | |
| SCHEMBL23547335 | 0.90 | CDK9 (0.51) | CDK9CDK4CDK7CDK2 | |
| SCHEMBL23547518 | 0.90 | CDK9 (0.49) | CDK9CDK4CDK7CDK2TLR9 | |
| SCHEMBL23547493 | 0.90 | CDK9 (0.49) | CDK9CDK4CDK7CDK2TLR9 | |
| SCHEMBL23547375 | 0.87 | CDK2 (0.45) | CDK9CDK4CDK7CDK2TLR9 | |
| SCHEMBL23547459 | 0.84 | CDK9 (0.49) | CDK9CDK4CDK7CDK2 | |
| SCHEMBL23547464 | 0.83 | ALDH1A1 (0.49) | CDK9CDK4CDK7CDK2 | |
| SCHEMBL20971693 | 0.81 | CDK9 (0.66) | CDK9CDK4CDK7CDK2TLR9 | |
| SCHEMBL20971705 | 0.81 | CDK9 (0.66) | CDK9CDK4CDK7CDK2TLR9 | |
| SCHEMBL31063988 | 0.81 | CDK2 (0.52) | CDK9CDK4CDK7CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021121390-A1 | HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, INTERMEDIATE THEREOF AND APPLICATION THEREOF | 苏州信诺维医药科技股份有限公司 | 2021-06-24 | — | — | WO | disclosed |