SCHEMBL23547996

SCHEMBL23547996

COCC1OC(n2cnc3c(NC(=O)c4ccccc4)ncnc32)C(OC)[C@@H]1OP(OCCC#N)N(C(C)C)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.44
P2RY12 Q9H244 8/20 0.40
ADORA1 P30542 2/20 0.39
P2RY2 P41231 1/20 0.38
P2RY1 P47900 1/20 0.38
P2RY6 Q15077 1/20 0.38
BMPR1B O00238 1/20 0.37
PRKAB2 O43741 1/20 0.37
PRKAG1 P54619 1/20 0.37
PRKAA2 P54646 1/20 0.37
PRKAA1 Q13131 1/20 0.37
PRKAG3 Q9UGI9 1/20 0.37
PRKAG2 Q9UGJ0 1/20 0.37
PRKAB1 Q9Y478 1/20 0.37
ADORA3 P0DMS8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23499883 1.00 PRMT6 (0.44) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL20248713 0.95 PRMT6 (0.45) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL26554337 0.95 PRMT6 (0.45) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL30209513 0.92 PRMT6 (0.41) PRMT6P2RY12ADORA1P2RY2P2RY1
SCHEMBL23547994 0.91 PRMT6 (0.42) PRMT6P2RY12ADORA1BMPR1B
SCHEMBL24878603 0.90 TYMP (0.43) PRMT6P2RY12ADORA1PRKAG1PRKAA1
SCHEMBL29581997 0.90 TYMP (0.43) PRMT6P2RY12ADORA1PRKAG1PRKAA1
SCHEMBL668595 0.90 TYMP (0.43) PRMT6P2RY12ADORA1PRKAG1PRKAA1
SCHEMBL25873876 0.90 TYMP (0.43) PRMT6P2RY12ADORA1PRKAG1PRKAA1
SCHEMBL26535891 0.90 TYMP (0.43) PRMT6P2RY12ADORA1PRKAG1PRKAA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210189392-A1 S-ANTIGEN TRANSPORT INHIBITING OLIGONUCLEOTIDE POLYMERS AND METHODS ALIGOS THERAPEUTICS, INC. 2021-06-24 US disclosed