Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 13/20 | 0.53 |
| ▸ | ADRB2 | P07550 | 12/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.53 |
| ▸ | DRD2 | P14416 | 2/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4458567 | 0.81 | ADRB2 (0.67) | ADRB3ADRB2ADRB1DRD2PGR | |
| SCHEMBL14118053 | 0.81 | ADRB2 (0.67) | ADRB3ADRB2ADRB1DRD2PGR | |
| SCHEMBL3628729 | 0.81 | ADRB2 (0.67) | ADRB3ADRB2ADRB1DRD2PGR | |
| SCHEMBL7182431 | 0.79 | ADRB2 (0.56) | ADRB3ADRB2ADRB1DRD2PGR | |
| SCHEMBL14118055 | 0.78 | ADRB2 (0.60) | ADRB3ADRB2ADRB1DRD2PGR | |
| SCHEMBL3412030 | 0.78 | ADRB2 (0.66) | ADRB3ADRB2ADRB1DRD2PGR | |
| SCHEMBL546271 | 0.77 | ADRB3 (0.73) | ADRB3ADRB2ADRB1DRD2PGR | |
| SCHEMBL9402466 | 0.77 | ADRB3 (0.73) | ADRB3ADRB2ADRB1DRD2PGR | |
| SCHEMBL30049456 | 0.77 | ADRB3 (0.73) | ADRB3ADRB2ADRB1DRD2PGR | |
| SCHEMBL2832807 | 0.74 | ADRB3 (0.56) | ADRB3ADRB2ADRB1DRD2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2355808-A2 | ARFORMOTEROL AND TIOTROPIUM COMPOSITIONS AND METHODS FOR USE | Sunovion Pharmaceuticals Inc. (US) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010048384-A2 | ARFORMOTEROL AND TIOTROPIUM COMPOSITIONS AND METHODS FOR USE | SEPRACOR INC. (US) | 2010-04-29 | — | — | WO | disclosed |
| EP-1643980-A1 | DRY POWDER FOR INHALATION COMPRISING A FORMOTEROL SALT AND CICLESONIDE | Aventis Pharma Limited (GB) | 2006-04-12 | — | — | EP | disclosed |
| WO-2005004853-A1 | DRY POWDER FOR INHALATION COMPRISING A FORMOTEROL SALT AND CICLESONIDE | AVENTIS PHARMA LIMITED (GB) | 2005-01-20 | — | — | WO | disclosed |
| EP-1446380-A1 | FORMOTEROL TARTRATE PROCESS AND POLYMORPH | Sepracor Inc. (US) | 2004-08-18 | — | — | EP | disclosed |
| WO-2003042165-A1 | FORMOTEROL TARTRATE PROCESS AND POLYMORPH | SEPRACOR INC. (US) | 2003-05-22 | — | — | WO | disclosed |
| EP-1093450-A1 | DESFORMOTEROL AND PROCESS FOR ITS PREPARATION | Sepracor Inc. (US) | 2001-04-25 | — | — | EP | disclosed |
| EP-1082293-A2 | FORMOTEROL POLYMORPHS | Sepracor Inc. (US) | 2001-03-14 | — | — | EP | disclosed |
| WO-2000067741-A2 | (S,R) FORMOTEROL METHODS AND COMPOSITIONS | SEPRACOR INC. (US) | 2000-11-16 | — | — | WO | disclosed |
| WO-2000021487-A2 | FORMOTEROL POLYMORPHS | SEPRACOR INC. (US) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999067198-A1 | DESFORMOTEROL AND PROCESS FOR ITS PREPARATION | SEPRACOR INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| EP-0938467-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE ISOMERS OF FORMOTEROL | SEPRACOR, INC. (US) | 1999-09-01 | — | — | EP | disclosed |
| WO-1998021175-A1 | PROCESS FOR THE PREPARATION OF OPTICALLY PURE ISOMERS OF FORMOTEROL | SEPRACOR, INC. (US) | 1998-05-22 | — | — | WO | disclosed |