Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 12/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 9/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 7/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.56 |
| ▸ | DRD3 | P35462 | 1/20 | 0.56 |
| ▸ | IGF1R | P08069 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3412030 | 0.82 | ADRB2 (0.66) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL3628729 | 0.81 | ADRB2 (0.67) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL4458567 | 0.81 | ADRB2 (0.67) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL14118053 | 0.81 | ADRB2 (0.67) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL16716731 | 0.81 | ADRB2 (0.54) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL15277792 | 0.80 | ADRB2 (0.69) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL2354898 | 0.79 | ADRB3 (0.53) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL10000683 | 0.78 | ADRB2 (0.69) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL8347843 | 0.78 | ADRB2 (0.69) | ADRB2ADRB3ADRB1DRD2PGR | |
| Fumaric Acid SCHEMBL29640688 | 0.78 | ADRB2 (0.64) | ADRB2ADRB3ADRB1DRD2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274433-A1 | MEDICAMENTS FOR TREATING RESPIRATORY DISORDERS COMPRISING FORMOTEROL AND FLUTICASONE | Innovata Biomed Limited (GB) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001078735-A1 | MEDICAMENTS FOR TREATING RESPIRATORY DISORDERS COMPRISING FORMOTEROL AND FLUTICASONE | INNOVATA BIOMED LIMITED (GB) | 2001-10-25 | — | — | WO | disclosed |