Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 13/20 | 0.67 |
| ▸ | ADRB3 | P13945 | 7/20 | 0.67 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.67 |
| ▸ | DRD2 | P14416 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 1/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | DRD3 | P35462 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14118053 | 1.00 | ADRB2 (0.67) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL3628729 | 1.00 | ADRB2 (0.67) | ADRB2ADRB3ADRB1DRD2PGR | |
| Fumaric Acid SCHEMBL29640688 | 0.85 | ADRB2 (0.64) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL8347843 | 0.83 | ADRB2 (0.69) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL10000683 | 0.83 | ADRB2 (0.69) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL3412030 | 0.83 | ADRB2 (0.66) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL7182431 | 0.81 | ADRB2 (0.56) | ADRB2ADRB3ADRB1DRD2PGR | |
| SCHEMBL2354898 | 0.81 | ADRB3 (0.53) | ADRB2ADRB3ADRB1DRD2PGR | |
| Formoterol SCHEMBL349579 | 0.81 | ADRB2 (1.00) | ADRB2ADRB3ADRB1DRD2PGR | |
| Arformoterol SCHEMBL6547706 | 0.81 | ADRB2 (1.00) | ADRB2ADRB3ADRB1DRD2PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4452222-A1 | DRY POWDER FORMULATIONS FILLED IN AN INHALER WITH IMPROVED RESISTANCE TO HUMIDITY | Chiesi Farmaceutici S.p.A. (IT) | 2024-10-30 | — | — | EP | disclosed |
| WO-2023117967-A1 | DRY POWDER FORMULATIONS FILLED IN AN INHALER WITH IMPROVED RESISTANCE TO HUMIDITY | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-06-29 | — | — | WO | disclosed |
| EP-3989971-A1 | NOVEL ANTIVIRAL THERAPIES | Niklovir AB (SE) | 2022-05-04 | — | — | EP | disclosed |
| WO-2020263151-A1 | NOVEL ANTIVIRAL THERAPIES | NIKLOVIR AB (SE) | 2020-12-30 | — | — | WO | disclosed |
| WO-2020152548-A1 | STABLE AEROSOL INHALATION COMPOSITIONS OF FORMOTEROL | GLENMARK PHARMACEUTICALS LIMITED (IN) | 2020-07-30 | — | — | WO | disclosed |
| EP-2076269-A2 | FORMULATIONS FOR TREATMENT OF ADIPOSE TISSUE, CUTANEOUS TISSUE AND DISORDERS, AND MUSCULAR TISSUE | Lithera, Inc. (US) | 2009-07-08 | — | — | EP | disclosed |
| WO-2008067060-A2 | FORMULATIONS FOR TREATMENT OF ADIPOSE TISSUE, CUTANEOUS TISSUE AND DISORDERS, AND MUSCULAR TISSUE | LITHERA, INC. (US) | 2008-06-05 | — | — | WO | disclosed |
| EP-0613371-A1 | NEW COMBINATION OF FORMOTEROL AND BUDESONIDE | Astra Aktiebolag (SE) | 1994-09-07 | — | — | EP | disclosed |
| WO-1993011773-A1 | NEW COMBINATION OF FORMOTEROL AND BUDESONIDE | AKTIEBOLAGET ASTRA (SE) | 1993-06-24 | — | — | WO | disclosed |
| US-5135954-A | Preventing or decreasing extravasation | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1992-08-04 | — | — | US | disclosed |