Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.71 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4457613 | 0.88 | LTA4H (0.55) | LTA4HMAOBCYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL570480 | 0.84 | LTA4H (1.00) | LTA4HSIGMAR1MEN1KMT2AHTT | |
| SCHEMBL28251912 | 0.82 | LTA4H (0.72) | LTA4HMAOBCYP11B1CYP11B2MEN1 | |
| SCHEMBL20930937 | 0.81 | CYP2C9 (0.60) | MEN1KMT2ALMNAMAPTHTT | |
| Nitrogen SCHEMBL28594721 | 0.80 | LTA4H (0.91) | LTA4HSIGMAR1MEN1KMT2AHTT | |
| SCHEMBL2027109 | 0.80 | LTA4H (0.69) | LTA4HMAOBCYP11B1CYP11B2MEN1 | |
| SCHEMBL5551078 | 0.79 | LTA4H (0.88) | LTA4HMAOBSIGMAR1MEN1KMT2A | |
| SCHEMBL984055 | 0.79 | LTA4H (0.67) | LTA4HMAOBCYP11B1CYP11B2SIGMAR1 | |
| SCHEMBL383153 | 0.78 | MEN1 (0.52) | LTA4HMAOBCYP11B1CYP11B2MEN1 | |
| SCHEMBL12869627 | 0.78 | LTA4H (0.60) | LTA4HMAOBCYP11B1CYP11B2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013126034-A1 | SYNTHESIS OF HIGH PURITY DMT-C3-DISULFIDE PHOSPHORAMIDITE | CHEMGENES CORPORATION (US) | 2013-08-29 | — | — | WO | claimed |
| EP-2560982-A2 | PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION | Chemgenes Corporation (US) | 2013-02-27 | — | — | EP | disclosed |
| WO-2011103468-A2 | PHOSPHORAMIDITES FOR SYNTHETIC RNA IN THE REVERSE DIRECTION | CHEMGENES CORPORATION (US) | 2011-08-25 | — | — | WO | disclosed |