SCHEMBL984055

SCHEMBL984055

COc1ccc(Cc2c3ccccc3c(Cc3ccc(OC)cc3)c3ccccc23)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.67
VKORC1 Q9BQB6 1/20 0.55
ALDH1A1 P00352 2/20 0.53
CYP2D6 P10635 1/20 0.53
ATM Q13315 1/20 0.53
LMNA P02545 1/20 0.53
SMN1; SMN2 Q16637 1/20 0.53
MAOB P27338 1/20 0.50
KDR P35968 2/20 0.49
IDO1 P14902 2/20 0.48
P2RX4 Q99571 1/20 0.47
MEN1 O00255 1/20 0.47
NSD2 O96028 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CYP11B1 P15538 1/20 0.47
CYP11B2 P19099 1/20 0.47
CA4 P22748 1/20 0.46
CA12 O43570 1/20 0.46
CA1 P00915 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14190048 0.83 LTA4H (0.47) LTA4HVKORC1MAOBKDRL3MBTL1
SCHEMBL18074057 0.81 LTA4H (0.53) LTA4HVKORC1ALDH1A1CYP2D6ATM
SCHEMBL570480 0.80 LTA4H (1.00) LTA4HIDO1MEN1KMT2AL3MBTL1
SCHEMBL27884 0.79 LTA4H (0.81) LTA4HALDH1A1CYP2D6ATMLMNA
SCHEMBL1425001 0.79 LTA4H (0.81) LTA4HALDH1A1CYP2D6ATMLMNA
SCHEMBL25986524 0.79 LTA4H (0.81) LTA4HALDH1A1CYP2D6ATMLMNA
SCHEMBL2355103 0.79 LTA4H (0.71) LTA4HALDH1A1LMNASMN1; SMN2MAOB
SCHEMBL28251912 0.78 LTA4H (0.72) LTA4HSMN1; SMN2MAOBIDO1MEN1
SCHEMBL8994737 0.78 VKORC1 (0.61) LTA4HVKORC1ALDH1A1LMNASMN1; SMN2
SCHEMBL20932951 0.78 LTA4H (0.50) LTA4HVKORC1ALDH1A1CYP2D6ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1786885-B1 ELECTROLUMINESCENT MATERIALS AND DEVICES MERCK PATENT GMBH (DE) 2011-05-18 EP claimed
US-20070252108-A1 Electroluminescent Materials and Devices MERCK PATENT GMBH (DE) 2007-11-01 US claimed
EP-2984079-B1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LTD (GB) 2020-07-01 EP disclosed
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices POWER OLEDS LIMITED (GB) 2019-10-08 US disclosed
US-20180323378-A9 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LIMITED (GB) 2018-11-08 US disclosed
EP-2232611-B1 BARRIER COATED SUBSTRATE AND ELECTRO-OPTICAL DEVICE MERCK PATENT GMBH (DE) 2017-11-01 EP disclosed
US-9437828-B2 Electroluminescent device using azomethine-lithium-complex as electron injection layer MERCK PATENT GMBH (DE) 2016-09-06 US disclosed
EP-2984079-A2 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES Power Oleds Limited (GB) 2016-02-17 EP disclosed
US-20160035983-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES POWER OLEDS LTD (GB) 2016-02-04 US disclosed
US-9221770-B2 Compounds having electron transport properties, their preparation and use MERCK PATENT GMBH (DE) 2015-12-29 US disclosed
EP-2318474-B1 COMPOUND HAVING ELECTROLUMINESCENT OR ELECTRON TRANSPORT PROPERTIES AND ITS PREPARATION AND USE MERCK PATENT GMBH (DE) 2015-05-27 EP disclosed
WO-2008078114-A1 ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2008-07-03 WO disclosed
WO-2008078115-A1 PHENANTHROLINE COMPOUNDS AND ELECTROLUMINESCENT DEVICES USING THE SAME MERCK PATENT GMBH (DE) 2008-07-03 WO disclosed
US-20080113215-A1 Electroluminescent Materials and Devices MERCK PATENT GMBH (DE) 2008-05-15 US disclosed
US-20080113215-A1 Electroluminescent Materials and Devices MERCK PATENT GMBH (DE) 2008-05-15 US disclosed
US-20080113215-A1 Electroluminescent Materials and Devices MERCK PATENT GMBH (DE) 2008-05-15 US disclosed
US-20070252108-A1 Electroluminescent Materials and Devices MERCK PATENT GMBH (DE) 2007-11-01 US disclosed
US-20070252108-A1 Electroluminescent Materials and Devices MERCK PATENT GMBH (DE) 2007-11-01 US disclosed
US-20070252108-A1 Electroluminescent Materials and Devices MERCK PATENT GMBH (DE) 2007-11-01 US disclosed
WO-2006090098-A1 ELECTROLUMINESCENT MATERIALS AND DEVICES OLED-T LIMITED (GB) 2006-08-31 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180323378-A9 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES NAT1, SLCO2A1, SLCO2B1 LTA4H 599/4885VKORC1 1199/4885ALDH1A1 789/4885
US-20070252108-A1 Electroluminescent Materials and Devices AAAS, ANXA1, ANXA2 LTA4H 2774/4885VKORC1 3534/4885ALDH1A1 1719/4885
US-10439147-B2 Heterocyclic compounds and their use in electro-optical or opto-electronic devices NAT1, SLCO2A1, SLCO2B1 LTA4H 599/4885VKORC1 1199/4885ALDH1A1 789/4885
US-20080113215-A1 Electroluminescent Materials and Devices AAAS, ACMSD, KCNH1 LTA4H 1593/4885VKORC1 3270/4885ALDH1A1 830/4885
US-20160035983-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE IN ELECTRO-OPTICAL OR OPTO-ELECTRONIC DEVICES NAT1, SLCO2A1, SLCO2B1 LTA4H 599/4885VKORC1 1199/4885ALDH1A1 789/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.