Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.62 |
| ▸ | CHRNA7 | P36544 | 3/20 | 0.58 |
| ▸ | HPGDS | O60760 | 2/20 | 0.55 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.53 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.53 |
| ▸ | KDM1A | O60341 | 3/20 | 0.52 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.50 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | NAMPT | P43490 | 2/20 | 0.46 |
| ▸ | ACSS2 | Q9NR19 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15327183 | 0.81 | NPC1 (0.53) | MAPK14HPGDSPDE4BPDE4D | |
| SCHEMBL561917 | 0.76 | TAS1R3 (0.60) | HPGDSKDM1ATDP1NAMPTACSS2 | |
| SCHEMBL10110571 | 0.76 | POLB (0.56) | MAPK14CHRNA7PDE4BTRPM8 | |
| SCHEMBL3362629 | 0.75 | HDAC6 (0.65) | CHRNA7TRPM8EGLN1 | |
| SCHEMBL6085312 | 0.75 | PLK1 (0.61) | MAPK14HPGDSPDE4BRIPK1HTR3A | |
| SCHEMBL30731032 | 0.75 | RIPK1 (0.56) | PDE4BPDE4DRIPK1 | |
| SCHEMBL5304873 | 0.75 | NPC1 (0.60) | HPGDSKDM1ATDP1NAMPT | |
| SCHEMBL6085305 | 0.75 | PLK1 (0.61) | MAPK14HPGDSPDE4BRIPK1HTR3A | |
| SCHEMBL24975649 | 0.75 | MMP9 (0.48) | MAPK14HPGDSPDE4BPDE4DKDM1A | |
| SCHEMBL31428468 | 0.75 | MMP9 (0.48) | MAPK14HPGDSPDE4BPDE4DKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2519504-A1 | NEW SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES. | Polichem SA (LU) | 2012-11-07 | — | — | EP | claimed |
| WO-2011080266-A1 | NEW SECONDARY 8-HYDROXYQUINOLINE-7-CARBOXAMIDE DERIVATIVES. | POLICHEM S.A. (LU) | 2011-07-07 | — | — | WO | claimed |