SCHEMBL23552257

SCHEMBL23552257

CC(C)=C1OC(C)=C(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)C1=O

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ SLC28A3 Q9HAS3 3/20 0.47
▸ HIF1A Q16665 1/20 0.46
▸ ALDH1A1 P00352 1/20 0.46
▸ POLB P06746 1/20 0.45
▸ ESR1 P03372 1/20 0.45
▸ ESR2 Q92731 1/20 0.45
▸ MEN1 O00255 1/20 0.45
▸ KMT2A Q03164 1/20 0.45
▸ PTPN1 P18031 1/20 0.44
▸ EPHX2 P34913 3/20 0.44
▸ TYR P14679 1/20 0.43
▸ SLC5A2 P31639 1/20 0.43
▸ CA12 O43570 3/20 0.42
▸ CA9 Q16790 3/20 0.42
▸ CA1 P00915 2/20 0.42
▸ CA2 P00918 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25632110 1.00 SLC28A3 (0.47) SLC28A3HIF1AALDH1A1POLBESR1
SCHEMBL25632421 0.83 POLB (0.49) SLC28A3HIF1AALDH1A1POLBESR1
SCHEMBL23552255 0.83 SLC5A1 (0.48) SLC28A3HIF1AESR1ESR2PTPN1
SCHEMBL23552399 0.79 SLC5A2 (0.30) SLC5A2
SCHEMBL31019029 0.77 SYNJ2 (0.39) ALDH1A1MEN1KMT2APTPN1SLC5A2
SCHEMBL26600978 0.74 ALDH1A1 (0.48) SLC28A3HIF1AALDH1A1POLBMEN1
SCHEMBL26601389 0.74 ALDH1A1 (0.48) SLC28A3HIF1AALDH1A1POLBMEN1
SCHEMBL22882206 0.72 ALDH1A1 (0.49) SLC28A3HIF1AALDH1A1POLBMEN1
SCHEMBL26601048 0.72 ALDH1A1 (0.49) SLC28A3HIF1AALDH1A1POLBMEN1
SCHEMBL26601099 0.70 ALDH1A1 (0.47) SLC28A3ALDH1A1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112999215-B Application of furanone glycoside compound 复旦大学 2024-06-21 — — CN disclosed
CN-113004355-B Furanone glycoside compound, pharmaceutical composition, preparation method and application thereof 复旦大学 2024-05-31 — — CN disclosed
US-11673909-B2 Furaneone glycoside compound, pharmaceutical composition thereof, preparation method therefor, and application thereof FUDAN UNIVERSITY (CN) 2023-06-13 — — US disclosed
US-11673909-B2 Furaneone glycoside compound, pharmaceutical composition thereof, preparation method therefor, and application thereof FUDAN UNIVERSITY (CN) 2023-06-13 — — US disclosed
US-11673909-B2 Furaneone glycoside compound, pharmaceutical composition thereof, preparation method therefor, and application thereof FUDAN UNIVERSITY (CN) 2023-06-13 — — US disclosed
US-20230092001-A1 FURANEOL GLYCOSIDE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FUDAN UNIVERSITY (CN) 2023-03-23 — — US disclosed
WO-2021121362-A1 FURANEOL GLYCOSIDE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF 复旦大学 2021-06-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230092001-A1 FURANEOL GLYCOSIDE COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND APPLICATION THEREOF FAR1, SFRP1, CYP4F11 SLC28A3 1376/4885HIF1A 4090/4885ALDH1A1 173/4885
US-11673909-B2 Furaneone glycoside compound, pharmaceutical composition thereof, preparation method therefor, and application thereof FAR1, CYP4A11, SFRP1 SLC28A3 2058/4885HIF1A 4079/4885ALDH1A1 136/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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