Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.40 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.40 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.40 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.40 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.40 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.37 |
| ▸ | SLC16A1 | P53985 | 2/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2355224 | 1.00 | LMNA (0.41) | LMNAMAPK1HTTRAB9APSEN1 | |
| SCHEMBL2690714 | 0.81 | PPARG (0.50) | LMNAMAPK1HTTRAB9APSEN1 | |
| SCHEMBL1587043 | 0.79 | CYP1A1 (0.46) | PPARG | |
| SCHEMBL1746959 | 0.79 | CYP1A1 (0.46) | PPARG | |
| SCHEMBL7825925 | 0.75 | KMT2A (0.61) | LMNAMAPK1RAB9ASLC16A3SLC16A1 | |
| SCHEMBL31118194 | 0.75 | POLB (0.45) | LMNARAB9APPARGKDM4EPKM | |
| SCHEMBL7825926 | 0.75 | KMT2A (0.61) | LMNAMAPK1RAB9ASLC16A3SLC16A1 | |
| SCHEMBL29279528 | 0.75 | PRKDC (0.42) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL27002115 | 0.75 | PRKDC (0.42) | LMNAPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL3501823 | 0.74 | PDE5A (0.39) | RAB9APPARGKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8008525-B2 | For the 14273 peroxisome proliferator activated receptor; antidiabetic agents, hyperlipidemia, obesity or anorexia; receptor binding assay; drug screening kits | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-08-30 | — | — | US | disclosed |