Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3501826 | 1.00 | PDE5A (0.39) | PDE5ANFE2L2SRCPOLBMAPT | |
| SCHEMBL31118194 | 0.86 | POLB (0.45) | NFE2L2POLBMAPTRAB9APPARG | |
| SCHEMBL1508505 | 0.84 | MEN1 (0.45) | PDE5ANFE2L2SRCPOLBMAPT | |
| SCHEMBL1508506 | 0.84 | MEN1 (0.45) | PDE5ANFE2L2SRCPOLBMAPT | |
| SCHEMBL1100701 | 0.83 | TBXAS1 (0.34) | POLBMAPTRAB9ATBXAS1PPARG | |
| SCHEMBL1100704 | 0.83 | TBXAS1 (0.34) | POLBMAPTRAB9ATBXAS1PPARG | |
| SCHEMBL3503013 | 0.82 | CYP4F2 (0.40) | TBXAS1PPARG | |
| SCHEMBL3503011 | 0.82 | CYP4F2 (0.40) | TBXAS1PPARG | |
| SCHEMBL3500595 | 0.81 | TBXAS1 (0.38) | TBXAS1PPARG | |
| SCHEMBL3500593 | 0.81 | TBXAS1 (0.38) | TBXAS1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100152165-A1 | CARBOXYLIC ACID DERIVATIVES | GPR119, GPR65, HCAR1 | PDE5A 2331/4885NFE2L2 2246/4885SRC 3054/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.