Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCP | P55072 | 4/20 | 0.54 |
| ▸ | KDR | P35968 | 8/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.44 |
| ▸ | FLT1 | P17948 | 7/20 | 0.43 |
| ▸ | FLT4 | P35916 | 7/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23553599 | 0.88 | GSK3B (0.47) | VCPKDRIMPDH2FLT1FLT4 | |
| SCHEMBL23540011 | 0.87 | VCP (0.53) | VCPKDRIMPDH2FLT1FLT4 | |
| SCHEMBL23539541 | 0.83 | VCP (0.55) | VCPKDRIMPDH2FLT1FLT4 | |
| SCHEMBL30042544 | 0.77 | VCP (0.61) | VCPKDRFLT1FLT4TRPV1 | |
| SCHEMBL23539613 | 0.77 | VCP (0.61) | VCPKDRFLT1FLT4TRPV1 | |
| SCHEMBL23539533 | 0.77 | VCP (0.72) | VCPKDRIMPDH2FLT1FLT4 | |
| SCHEMBL21303771 | 0.76 | VCP (0.59) | VCPKDRIMPDH2FLT1FLT4 | |
| SCHEMBL23539561 | 0.74 | CACNA1B (0.46) | VCPKDRFLT1FLT4TRPV1 | |
| SCHEMBL21303787 | 0.74 | VCP (0.76) | VCPKDRIMPDH2FLT1FLT4 | |
| SCHEMBL26307279 | 0.72 | FLT1 (0.52) | VCPKDRIMPDH2FLT1FLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | Ikena Oncology, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20230295147-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | ARYL THERAPEUTICS, INC. | 2023-09-21 | — | — | US | disclosed |
| WO-2021127301-A1 | 4-PHENYL-N-(PHENYL)THIAZOL-2-AMINE DERIVATIVES AND RELATED COMPOUNDS AS ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS FOR THE TREATMENT OF E.G. ANGIOGENESIS IMPLICATED OR INFLAMMATORY DISORDERS | Ikena Oncology, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | AHR, ARNT, HCAR1 | VCP 2673/4885KDR 867/4885IMPDH2 2316/4885 |
| US-20230295147-A1 | ARYL HYDROCARBON RECEPTOR (AHR) AGONISTS AND USES THEREOF | AHR, ARNT, HCAR1 | VCP 2673/4885KDR 867/4885IMPDH2 2316/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.