SCHEMBL23554367

SCHEMBL23554367

COc1cc(-c2cc(C(F)(F)F)cc(C(F)(F)F)c2)cc(OC)c1-c1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1C3 P42330 1/20 0.42
AKR1C2 P52895 1/20 0.42
IKBKB O14920 1/20 0.41
CTSA P10619 2/20 0.40
CNR2 P34972 3/20 0.39
NPSR1 Q6W5P4 1/20 0.38
RXRA P19793 3/20 0.38
RXRB P28702 3/20 0.38
RXRG P48443 2/20 0.38
KIF11 P52732 1/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD17B10 Q99714 1/20 0.38
F2RL3 Q96RI0 1/20 0.37
AR P10275 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23554365 0.85 AR (0.51) AKR1C3AKR1C2CTSANPSR1KDM4E
SCHEMBL3294707 0.78 AKR1C3 (0.54) AKR1C3AKR1C2CTSANPSR1SMN1; SMN2
SCHEMBL27910087 0.77 KIF11 (0.45) AKR1C3AKR1C2CNR2NPSR1KIF11
SCHEMBL9482063 0.75 RXRA (0.54) IKBKBCNR2RXRARXRBRXRG
SCHEMBL14499450 0.74 RXRA (0.54) AKR1C3AKR1C2NPSR1RXRARXRB
SCHEMBL23554368 0.74 ABCG2 (0.41) AKR1C3AKR1C2NPSR1RXRARXRB
SCHEMBL12964117 0.73 AKR1C3 (0.41) AKR1C3AKR1C2IKBKBCTSANPSR1
SCHEMBL28441006 0.73 AKR1C3 (0.50) AKR1C3AKR1C2IKBKBCTSANPSR1
SCHEMBL13866628 0.72 RXRA (0.52) IKBKBCNR2RXRARXRBRXRG
SCHEMBL13247923 0.72 RXRA (0.55) RXRARXRBRXRGKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210189077-A1 THIN FILM MATERIAL AND MANUFACTURING METHOD OF THIN FILM MATERIAL WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2021-06-24 US disclosed
WO-2021120348-A1 THIN FILM MATERIAL AND PREPARATION METHOD FOR THIN FILM MATERIAL 武汉华星光电半导体显示技术有限公司 2021-06-24 WO disclosed