Phosphocholine

Phosphocholine

SCHEMBL2355628

C[N+](C)(C)CCOP(=O)(O)O.[Cl-].[NaH]

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Phosphocholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 known ✓ P11229 6/20 0.45
CHRM3 known ✓ P20309 6/20 0.45
CHRM2 known ✓ P08172 5/20 0.43
ACHE known ✓ P22303 1/20 0.38
CHRM5 P08912 6/20 0.45
BBOX1 O75936 2/20 0.45
MAPT P10636 1/20 0.45
BLM P54132 1/20 0.45
CHRM4 P08173 5/20 0.43
LPAR3 Q9UBY5 3/20 0.43
LPAR1 Q92633 2/20 0.43
LPAR2 Q9HBW0 2/20 0.43
SMN1; SMN2 Q16637 3/20 0.43
LMNA P02545 3/20 0.43
ADRA1A P35348 2/20 0.43
ESR1 P03372 1/20 0.43
ADORA3 P0DMS8 1/20 0.43
CDC25A P30304 1/20 0.43
AGTR1 P30556 1/20 0.43
AKT1 P31749 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phosphocholine SCHEMBL27662115 0.98 LPAR3 (0.45) CHRM5CHRM1CHRM3BBOX1MAPT
Phosphocholine SCHEMBL30080880 0.98 CHRM5 (0.46) CHRM5CHRM1CHRM3BBOX1MAPT
Phosphocholine SCHEMBL24426 0.98 CHRM5 (0.46) CHRM5CHRM1CHRM3BBOX1MAPT
Phosphocholine SCHEMBL30570440 0.95 CHRM5 (0.45) CHRM5CHRM1CHRM3BBOX1MAPT
Phosphocholine SCHEMBL20838517 0.95 CHRM5 (0.45) CHRM5CHRM1CHRM3BBOX1MAPT
Phosphocholine SCHEMBL5143798 0.95 CHRM5 (0.45) CHRM5CHRM1CHRM3BBOX1MAPT
Phosphocholine SCHEMBL29533477 0.95 CHRM5 (0.45) CHRM5CHRM1CHRM3BBOX1MAPT
Phosphocholine SCHEMBL933392 0.95 CHRM5 (0.45) CHRM5CHRM1CHRM3BBOX1MAPT
Phosphocholine SCHEMBL10717805 0.95 CHRM5 (0.45) CHRM5CHRM1CHRM3BBOX1MAPT
Phosphocholine SCHEMBL18662889 0.95 CHRM5 (0.45) CHRM5CHRM1CHRM3BBOX1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6773822-B2 ANTIFUNGAL AGENT MAY BE PRESENT IN THE GYPSUM CORE AND/OR ON ONE OR BOTH OF THE PAPER FACINGS, AND MAY BE ENCAPSULATED IN A MATERIAL THAT RELEASES THE ANTIFUNGAL AGENT OVER TIME AND/OR UPON EXPOSURE TO MOISTURE. TEMPLE-INLAND FOREST PRODUCTS CORPORATION 2004-08-10 US claimed
EP-0146017-A1 Plant growth regulator and method for increasing crop yields and promoting root formation MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-06-26 EP claimed
JP-62042907-A None JP disclosed
US-20230279266-A1 POLISHING LIQUID COMPOSITION FOR SILICON OXIDE FILMS KAO CORPORATION (JP) 2023-09-07 US disclosed
EP-2905361-B1 METHOD OF FORMING A METAL COATING TOYOTA MOTOR CO LTD (JP) 2022-01-05 EP disclosed
US-9708723-B2 Electroplating cell, and metal coating and method of forming the same TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2017-07-18 US disclosed
EP-2905361-A1 ELECTROPLATING CELL, METAL COATING AND METHOD OF FORMING THE SAME Toyota Jidosha Kabushiki Kaisha (JP) 2015-08-12 EP disclosed
US-20150218723-A1 ELECTROPLATING CELL, AND METAL COATING AND METHOD OF FORMING THE SAME TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) 2015-08-06 US disclosed
US-8653156-B2 Composite material having the appearance of natural stone Consentino, S.A. (ES) 2014-02-18 US disclosed
US-8007921-B2 Gypsum board containing antimicrobial and antibacterial compounds QUICK-MED TECHNOLOGIES, INC. (US) 2011-08-30 US disclosed
US-20100311865-A1 Gypsum Board Containing Antimicrobial And Antibacterial Compounds QUICK-MED TECHNOLOGIES, INC. (US) 2010-12-09 US disclosed
US-20030035981-A1 Antifungal gypsum board TIN INC. D/B/A TEMPLE-INLAND 2003-02-20 US disclosed
WO-2003012218-A1 ANTIFUNGAL GYPSUM BOARD TEMPLE-INLAND FOREST PRODUCTS CORPORATION (US) 2003-02-13 WO disclosed
US-20030031898-A1 Antifungal gypsum board TIN INC. D/B/A TEMPLE-INLAND 2003-02-13 US disclosed
EP-0421666-B1 Thermosetting resin composition DAINIPPON INK & CHEMICALS (JP) 1996-01-24 EP disclosed
US-5393855-A Containing a 2-oxo-1,3-dioxolan-4-yl group DAINIPPON INK AND CHEMICALS, INC. (JP) 1995-02-28 US disclosed
US-5374699-A Vinyl polymer having 2-oxo-1,3-dioxolan-4-yl group and carboxyl group and a ring opening catalyst; coatings DAINIPPONINK AND CHEMICALS, INC. (JP) 1994-12-20 US disclosed
EP-0421666-A2 Thermosetting resin composition DAINIPPON INK AND CHEMICALS, INC. (JP) 1991-04-10 EP disclosed
JP-S6242907-A PHYTOTOXICITY REDUCING AGENT FOR RICE PLANT MITSUBISHI GAS CHEM CO INC 1987-02-24 JP disclosed
EP-0146017-A1 Plant growth regulator and method for increasing crop yields and promoting root formation MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1985-06-26 EP disclosed