Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Phosphocholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.45 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.45 |
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.43 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 6/20 | 0.45 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.43 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphocholine SCHEMBL18315379 | 0.98 | CHRM5 (0.43) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL30080880 | 0.98 | CHRM5 (0.46) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL24426 | 0.98 | CHRM5 (0.46) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL18037433 | 0.98 | LPAR3 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL5143798 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL30570440 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL10717805 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL2355628 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL20838517 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL18662889 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117551147-A | Synthetic method of citicoline | 成都市海通药业有限公司 | 2024-02-13 | — | — | CN | claimed |
| CN-116939986-A | Improvement process for circuit board nickel-gold plating | 龙南骏亚柔性智能科技有限公司 | 2023-10-24 | — | — | CN | claimed |
| CN-116768948-A | Method for synthesizing urine phosphorylcholine in citicoline injection | 山东玉满坤生物科技有限公司 | 2023-09-19 | — | — | CN | claimed |
| CN-108546273-B | Novel process for preparing phosphorylcholine chloride calcium salt | 浙江云涛生物技术股份有限公司 | 2020-12-15 | — | — | CN | claimed |
| CN-108610359-B | Preparation method of phosphorylcholine chloride calcium salt | 山东奥博生物科技有限公司 | 2020-05-29 | — | — | CN | claimed |
| CN-210237505-U | Phosphorylcholine calcium chloride salt production system | RUGAO ZHONGCHANG CHEMICAL CO., LTD. | 2020-04-03 | — | — | CN | claimed |
| US-6773822-B2 | ANTIFUNGAL AGENT MAY BE PRESENT IN THE GYPSUM CORE AND/OR ON ONE OR BOTH OF THE PAPER FACINGS, AND MAY BE ENCAPSULATED IN A MATERIAL THAT RELEASES THE ANTIFUNGAL AGENT OVER TIME AND/OR UPON EXPOSURE TO MOISTURE. | TEMPLE-INLAND FOREST PRODUCTS CORPORATION | 2004-08-10 | — | — | US | claimed |
| EP-4393934-A1 | METHOD FOR PRODUCING CYTIDINE-5'-DIPHOSPHATE COMPOUND | Kyowa Hakko Bio Co., Ltd. (JP) | 2024-07-03 | — | — | EP | disclosed |
| CN-117551147-A | Synthetic method of citicoline | 成都市海通药业有限公司 | 2024-02-13 | — | — | CN | disclosed |
| CN-113816991-B | Preparation method of choline calcium chloride phosphate | 拓新药业集团股份有限公司 | 2023-12-15 | — | — | CN | disclosed |
| US-20230365602-A1 | COMPOUND FOR USE IN THE TREATMENT OF PROTOZOAL DISEASES AND PROCESS FOR PRODUCTION OF SAID COMPOUND | QUADREL S.R.L. (IT) | 2023-11-16 | — | — | US | disclosed |
| CN-117024473-A | Preparation method of L-alpha-phosphorylcholine | 沈阳金久奇科技有限公司 | 2023-11-10 | — | — | CN | disclosed |
| WO-2023211988-A2 | COMPOSITIONS AND METHODS FOR ANTI-PHOSPHOCHOLINE ACTIVE IMMUNOTHERAPY | DUKE UNIVERSITY (US) | 2023-11-02 | — | — | WO | disclosed |
| WO-2003012218-A1 | ANTIFUNGAL GYPSUM BOARD | TEMPLE-INLAND FOREST PRODUCTS CORPORATION (US) | 2003-02-13 | — | — | WO | disclosed |
| US-20030031898-A1 | Antifungal gypsum board | TIN INC. D/B/A TEMPLE-INLAND | 2003-02-13 | — | — | US | disclosed |
| EP-0076515-B1 | RAPIDLY RELEASABLE MICROCAPSULES AND METHOD FOR THE PREPARATION THEREOF | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |
| EP-0077956-B1 | ENTERIC MICROCAPSULES AND PROCESS FOR THE PREPARATION THEREOF | Tanabe Seiyaku Co., Ltd. (JP) | 1985-07-03 | — | — | EP | disclosed |
| EP-0146017-A1 | Plant growth regulator and method for increasing crop yields and promoting root formation | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 1985-06-26 | — | — | EP | disclosed |
| EP-0077956-A1 | Enteric microcapsules and process for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1983-05-04 | — | — | EP | disclosed |
| EP-0076515-A1 | Rapidly releasable microcapsules and method for the preparation thereof | Tanabe Seiyaku Co., Ltd. (JP) | 1983-04-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230365602-A1 | COMPOUND FOR USE IN THE TREATMENT OF PROTOZOAL DISEASES AND PROCESS FOR PRODUCTION OF SAID COMPOUND | PIGO, PIGS, AGPS | CHRM1 4491/4885CHRM3 4406/4885CHRM2 4302/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.