Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Phosphocholine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 known ✓ | P08912 | 6/20 | 0.45 |
| ▸ | CHRM1 known ✓ | P11229 | 6/20 | 0.45 |
| ▸ | CHRM3 known ✓ | P20309 | 6/20 | 0.45 |
| ▸ | CHRM2 known ✓ | P08172 | 5/20 | 0.43 |
| ▸ | CHRM4 known ✓ | P08173 | 5/20 | 0.43 |
| ▸ | ADRA1A known ✓ | P35348 | 2/20 | 0.43 |
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.43 |
| ▸ | ADORA3 known ✓ | P0DMS8 | 1/20 | 0.43 |
| ▸ | AGTR1 known ✓ | P30556 | 1/20 | 0.43 |
| ▸ | HTR1A known ✓ | P08908 | 2/20 | 0.41 |
| ▸ | ADRA2A known ✓ | P08913 | 1/20 | 0.41 |
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.38 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | LPAR3 | Q9UBY5 | 3/20 | 0.43 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phosphocholine SCHEMBL18662889 | 1.00 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL18315379 | 0.98 | CHRM5 (0.43) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL18315378 | 0.98 | CHRM5 (0.43) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL24426 | 0.98 | CHRM5 (0.46) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL17373733 | 0.98 | LPAR3 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL30080880 | 0.98 | CHRM5 (0.46) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL2355628 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL5143798 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL20838517 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT | |
| Phosphocholine SCHEMBL10717805 | 0.95 | CHRM5 (0.45) | CHRM5CHRM1CHRM3BBOX1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230279266-A1 | POLISHING LIQUID COMPOSITION FOR SILICON OXIDE FILMS | KAO CORPORATION (JP) | 2023-09-07 | — | — | US | disclosed |
| CN-116323843-A | Polishing composition for silicon oxide film | 花王株式会社 | 2023-06-23 | — | — | CN | disclosed |
| WO-2022075179-A1 | POLISHING LIQUID COMPOSITION FOR SILICON OXIDE FILMS | 花王株式会社 | 2022-04-14 | — | — | WO | disclosed |