SCHEMBL2355679

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL10173670	0.92	PTGES (0.47)	PTGESP2RX7MEN1CYP1A2CYP2D6
	SCHEMBL2364015	0.92	PTGES (0.42)	PTGESP2RX7MEN1CYP1A2CYP2D6
	SCHEMBL2356902	0.89	PTGES (0.49)	PTGESP2RX7MEN1CYP1A2CYP2D6
	SCHEMBL10173624	0.85	PTGES (0.47)	PTGESP2RX7HSD17B13
	SCHEMBL2363941	0.84	PTGES (0.42)	PTGESP2RX7MEN1CYP1A2CYP2D6
	SCHEMBL10173604	0.83	PTGES (0.38)	PTGES
	SCHEMBL2683760	0.82	PTGES (0.41)	PTGES
	SCHEMBL2683766	0.82	PTGES (0.38)	PTGES
	SCHEMBL2683837	0.82	PTGES (0.44)	PTGESMEN1HPGDKMT2AHSD17B13
	SCHEMBL2302522	0.82	PTGES (0.49)	PTGESP2RX7MEN1CYP1A2CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.