Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 10/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23557979 | 0.97 | GRIN2B (0.46) | MAPTPTGS2GRIN2BPOLBGRIN1 | |
| SCHEMBL23531695 | 0.80 | EGLN1 (0.48) | PTGS2POLBALDH1A1 | |
| SCHEMBL21603319 | 0.79 | GRIN2B (0.48) | GRIN2B | |
| SCHEMBL21603316 | 0.76 | GRIN2B (0.50) | GRIN2B | |
| SCHEMBL29825072 | 0.76 | GRIN2B (0.44) | GRIN2BGRIN1 | |
| SCHEMBL23531724 | 0.76 | GRIN2B (0.44) | GRIN2BGRIN1 | |
| SCHEMBL30015306 | 0.73 | FPR2 (0.43) | POLBALDH1A1KMT2A | |
| SCHEMBL23558005 | 0.73 | FPR2 (0.43) | POLBALDH1A1KMT2A | |
| SCHEMBL23557976 | 0.73 | GRIN2B (0.43) | GRIN2BGRIN1ALDH1A1KMT2A | |
| SCHEMBL15416672 | 0.72 | LMNA (0.67) | PTGS2GRIN2BALDH1A1GAACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021123294-A1 | OGA INHIBITOR COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2021-06-24 | — | — | WO | disclosed |