Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.47 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.47 |
| ▸ | CHUK | O15111 | 2/20 | 0.41 |
| ▸ | TXNRD1 | Q16881 | 2/20 | 0.41 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23524176 | 0.93 | CASP3 (0.48) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL29673234 | 0.84 | SMN1; SMN2 (0.51) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL25864495 | 0.83 | CASP3 (0.45) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL23558447 | 0.83 | HSD17B1 (0.37) | NPC1HPGDRAB9AMAPTKDM4E | |
| SCHEMBL23558569 | 0.83 | CASP3 (0.52) | CASP3SENP8SENP7SENP6CHUK | |
| SCHEMBL30355704 | 0.81 | SMN1; SMN2 (0.45) | NPC1HSD17B10HPGDRAB9AMAPT | |
| SCHEMBL30355631 | 0.81 | NPC1 (0.51) | NPC1HSD17B10RAB9AMAPTMEN1 | |
| SCHEMBL23524293 | 0.81 | NPC1 (0.51) | NPC1HSD17B10RAB9AMAPTMEN1 | |
| SCHEMBL23523886 | 0.81 | SMN1; SMN2 (0.45) | NPC1HSD17B10HPGDRAB9AMAPT | |
| SCHEMBL25863145 | 0.81 | CASP3 (0.49) | CASP3SENP8SENP7SENP6CHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | CASP3 3079/4885SENP8 3546/4885SENP7 3962/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.