Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | ENPP3 | O14638 | 3/20 | 0.36 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.35 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | TDO2 | P48775 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25862898 | 0.93 | HCAR3 (0.42) | HSD17B1HSD17B2ENPP3ENPP1KCNMA1 | |
| SCHEMBL23558259 | 0.83 | CASP3 (0.47) | KCNMA1HCAR3HPGDHCAR2MEN1 | |
| SCHEMBL30355461 | 0.82 | ENPP3 (0.47) | HSD17B1HSD17B2ENPP3ENPP1HCAR3 | |
| SCHEMBL23524018 | 0.82 | ENPP3 (0.47) | HSD17B1HSD17B2ENPP3ENPP1HCAR3 | |
| SCHEMBL30355543 | 0.81 | HPGD (0.39) | HSD17B1HSD17B2ENPP3ENPP1HCAR3 | |
| SCHEMBL30355828 | 0.81 | HPGD (0.39) | HSD17B1HSD17B2ENPP3ENPP1HCAR3 | |
| SCHEMBL23524141 | 0.81 | HPGD (0.39) | HSD17B1HSD17B2ENPP3ENPP1HCAR3 | |
| SCHEMBL23524066 | 0.81 | HPGD (0.39) | HSD17B1HSD17B2ENPP3ENPP1HCAR3 | |
| SCHEMBL23523960 | 0.81 | HPGD (0.39) | HSD17B1HSD17B2ENPP3ENPP1HCAR3 | |
| SCHEMBL27100035 | 0.81 | HPGD (0.39) | HSD17B1HSD17B2ENPP3ENPP1HCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | HSD17B1 2149/4885HSD17B2 2368/4885ENPP3 528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.