Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.37 |
| ▸ | GAA | P10253 | 8/20 | 0.37 |
| ▸ | HPGD | P15428 | 5/20 | 0.37 |
| ▸ | GLA | P06280 | 4/20 | 0.37 |
| ▸ | CASP1 | P29466 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | CASP7 | P55210 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.35 |
| ▸ | MMP13 | P45452 | 4/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23558464 | 0.83 | ACACB (0.37) | ACACBENPP3ENPP1HSD17B1HSD17B2 | |
| SCHEMBL25863741 | 0.75 | ACACB (0.37) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL23558565 | 0.73 | NPC1 (0.42) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL23558458 | 0.72 | MMP13 (0.40) | KDM4EALDH1A1GAAHPGDGLA | |
| SCHEMBL25856816 | 0.72 | ACACB (0.35) | KDM4EACACBHSD17B1HSD17B2 | |
| SCHEMBL23558336 | 0.70 | CNR1 (0.35) | ACACBENPP3ENPP1MMP13HSD17B1 | |
| SCHEMBL23558412 | 0.69 | TPH1 (0.42) | KDM4EALDH1A1HPGDHSD17B10NPC1 | |
| SCHEMBL23524238 | 0.68 | NPC1 (0.44) | ALDH1A1GAAHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL23558300 | 0.68 | PPM1D (0.37) | ACACBMMP13 | |
| SCHEMBL23558568 | 0.67 | HSD17B1 (0.46) | KDM4EALDH1A1HPGDKLK7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | TREVENA, INC. | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188826-A1 | COMPOUNDS FOR MODULATING S1P1 ACTIVITY AND METHODS OF USING THE SAME | S1PR1, S1PR2, S1PR3 | KDM4E 2644/4885ALDH1A1 2583/4885GAA 3859/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.