Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 6/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21993355 | 0.91 | EGLN1 (0.41) | EGLN1OPRM1OPRK1OPRL1BACE1 | |
| SCHEMBL2525874 | 0.84 | BACE1 (0.39) | EGLN1OPRM1BACE1 | |
| SCHEMBL12582456 | 0.79 | EGLN1 (0.70) | EGLN1 | |
| SCHEMBL30485278 | 0.77 | EGLN1 (0.34) | EGLN1BACE1KCNH2 | |
| SCHEMBL14668941 | 0.77 | BACE1 (0.34) | EGLN1BACE1KCNH2 | |
| SCHEMBL8053306 | 0.75 | OPRL1 (0.61) | EGLN1OPRM1OPRK1OPRL1 | |
| SCHEMBL3519201 | 0.74 | LMNA (0.37) | BACE1 | |
| SCHEMBL1700112 | 0.73 | CALCA (0.49) | — | |
| SCHEMBL8687319 | 0.73 | LMNA (0.35) | BACE1KCNH2 | |
| SCHEMBL25890242 | 0.72 | ADORA3 (0.37) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127328-A1 | TRPML MODULATORS | CASMA THERAPEUTICS, INC. (US) | 2021-06-24 | — | — | WO | disclosed |