Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.50 |
| ▸ | NAMPT | P43490 | 4/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25401294 | 0.94 | GPR119 (0.44) | GPR119NAMPT | |
| SCHEMBL22797267 | 0.90 | OXTR (0.42) | GPR119NAMPTPOLB | |
| SCHEMBL388491 | 0.86 | KDM4E (0.47) | GPR119 | |
| SCHEMBL20642053 | 0.86 | GPR119 (0.50) | GPR119NAMPT | |
| SCHEMBL20919479 | 0.85 | CHRNB2 (0.39) | GPR119 | |
| SCHEMBL20920037 | 0.84 | GPR119 (0.49) | GPR119NAMPTPOLB | |
| SCHEMBL23559105 | 0.82 | GPR119 (0.46) | GPR119NAMPT | |
| SCHEMBL23558620 | 0.81 | NAMPT (0.53) | GPR119NAMPT | |
| SCHEMBL24608255 | 0.80 | NR1H2 (0.52) | GPR119NAMPTPOLB | |
| SCHEMBL23545096 | 0.80 | NR1H2 (0.52) | GPR119NAMPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11149022-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | VANDERBILT UNIVERSITY (US) | 2021-10-19 | — | — | US | disclosed |
| US-20210188811-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | VANDERBILT UNIVERSITY | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188811-A1 | ANTAGONISTS OF THE MUSCARINIC ACETYLCHOLINE RECEPTOR M4 | CHRM2, CHRM3, CHRM4 | GPR119 84/4885NAMPT 1938/4885POLB 3513/4885 |
| US-11149022-B2 | Antagonists of the muscarinic acetylcholine receptor M4 | CHRM2, CHRM3, CHRM4 | GPR119 84/4885NAMPT 1938/4885POLB 3513/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.