Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 12/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543717 | 1.00 | OPRM1 (0.34) | OPRM1OPRK1OGFRL1SMN1; SMN2NPSR1 | |
| SCHEMBL17586630 | 1.00 | OPRM1 (0.34) | OPRM1OPRK1OGFRL1SMN1; SMN2NPSR1 | |
| SCHEMBL25919584 | 0.89 | MAPT (0.35) | OPRM1OPRK1OGFRL1SMN1; SMN2NPSR1 | |
| SCHEMBL17583055 | 0.88 | IDH1 (0.37) | OPRM1OPRK1OGFRL1IDH1ALK | |
| SCHEMBL17583059 | 0.88 | IDH1 (0.37) | OPRM1OPRK1OGFRL1IDH1ALK | |
| SCHEMBL17582767 | 0.83 | MAPT (0.38) | OPRM1OPRK1OGFRL1SMN1; SMN2NPSR1 | |
| SCHEMBL30659144 | 0.83 | MAPT (0.38) | OPRM1OPRK1OGFRL1SMN1; SMN2NPSR1 | |
| SCHEMBL25922214 | 0.83 | OPRM1 (0.35) | OPRM1OPRK1OGFRL1SMN1; SMN2NPSR1 | |
| SCHEMBL17582993 | 0.83 | ALK (0.36) | IDH1ALKEGFR | |
| SCHEMBL17582904 | 0.80 | NPSR1 (0.39) | OPRM1OPRK1OGFRL1SMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210188782-A1 | BENZOIMIDAZOL-1,2-YL AMIDES AS Kv7 CHANNEL ACTIVATORS | CHANNEL BIOSCIENCES, LLC | 2021-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210188782-A1 | BENZOIMIDAZOL-1,2-YL AMIDES AS Kv7 CHANNEL ACTIVATORS | KCNA7, KCNJ2, KCNK17 | OPRM1 1026/4885OPRK1 217/4885OGFRL1 1251/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.