Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | IDH1 | O75874 | 13/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30543717 | 0.89 | OPRM1 (0.34) | MAPTMAPK1IDH1OPRM1OPRK1 | |
| SCHEMBL23559787 | 0.89 | OPRM1 (0.34) | MAPTMAPK1IDH1OPRM1OPRK1 | |
| SCHEMBL17586630 | 0.89 | OPRM1 (0.34) | MAPTMAPK1IDH1OPRM1OPRK1 | |
| SCHEMBL17582767 | 0.86 | MAPT (0.38) | MAPTMAPK1OPRM1OPRK1OGFRL1 | |
| SCHEMBL30659144 | 0.86 | MAPT (0.38) | MAPTMAPK1OPRM1OPRK1OGFRL1 | |
| SCHEMBL20110774 | 0.83 | ALK (0.35) | IDH1ALKEGFR | |
| SCHEMBL25922214 | 0.83 | OPRM1 (0.35) | MAPTMAPK1OPRM1OPRK1OGFRL1 | |
| SCHEMBL17582904 | 0.79 | NPSR1 (0.39) | MAPTMAPK1OPRM1OPRK1OGFRL1 | |
| SCHEMBL25922209 | 0.78 | MAPT (0.35) | MAPTMAPK1IDH1OPRM1OPRK1 | |
| SCHEMBL17583055 | 0.77 | IDH1 (0.37) | IDH1OPRM1OPRK1OGFRL1ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3572405-B1 | BENZOIMIDAZOL-1,2-YL AMIDES AS KV7 CHANNEL ACTIVATORS | KNOPP BIOSCIENCES LLC (US) | 2023-07-26 | — | — | EP | disclosed |