SCHEMBL11587461

SCHEMBL11587461

Cc1ccccc1OC1(C)CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.38
P2RX7 Q99572 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
TSHR P16473 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
NPC1 O15118 1/20 0.37
RAB9A P51151 1/20 0.37
ALDH1A1 P00352 1/20 0.37
GLA P06280 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37
HDAC4 P56524 1/20 0.34
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ACHE P22303 1/20 0.33
DRD2 P14416 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1839819 0.79 TP53 (0.45) TDP1MEN1KMT2ATSHRSMN1; SMN2
SCHEMBL13672476 0.78 DRD2 (0.44) SLC6A4DRD2
SCHEMBL1836784 0.77 TP53 (0.47) TDP1KMT2ATSHRSMN1; SMN2NPC1
SCHEMBL8784979 0.77 ALDH1A1 (0.47) TDP1MEN1KMT2ASMN1; SMN2ALDH1A1
SCHEMBL16359413 0.77 TDP1 (0.38) TDP1MEN1KMT2ATSHRSMN1; SMN2
SCHEMBL13564264 0.75 DRD2 (0.45) TSHRSLC6A4DRD2
SCHEMBL5355485 0.75 ALDH1A1 (0.33) P2RX7ALDH1A1DRD2
SCHEMBL10432441 0.75 KDM4E (0.38) TDP1P2RX7MEN1KMT2ATSHR
SCHEMBL11060996 0.74 SLC6A2 (0.43) MEN1KMT2ARAB9AALDH1A1SLC6A2
SCHEMBL8036350 0.74 KDM4E (0.49) TDP1MEN1KMT2ATSHRALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4113782-A CATALYTIC OXIDATION AGENCY OF INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 1978-09-12 US disclosed