Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 2/20 | 0.40 |
| ▸ | CDK1 | P06493 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7058435 | 0.82 | CA12 (0.47) | ALDH1A1GAATDP1KDM4ELMNA | |
| SCHEMBL16639670 | 0.82 | KMT2A (0.54) | ALDH1A1TDP1KDM4ELMNAHSD17B10 | |
| SCHEMBL8036267 | 0.81 | KDM4E (0.62) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL23560900 | 0.80 | ALDH1A1 (0.43) | ALDH1A1KDM4ELMNAHSD17B10MEN1 | |
| SCHEMBL17747120 | 0.79 | CA1 (0.54) | ALDH1A1GAATDP1KDM4ELMNA | |
| SCHEMBL15858102 | 0.77 | KDM4E (0.61) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL11362354 | 0.77 | KDM4E (0.58) | ALDH1A1GAATDP1KDM4ELMNA | |
| SCHEMBL18748417 | 0.76 | KDM4E (0.55) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL13229315 | 0.75 | KDM4E (0.56) | ALDH1A1KDM4ELMNAHSD17B10MAPT | |
| SCHEMBL106447 | 0.75 | CYP2C19 (0.43) | MEN1KMT2ASTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127214-A1 | SYNTHETIC PROCESSES AND INTERMEDIATES | ARBUTUS BIOPHARMA CORPORATION (CA) | 2021-06-24 | — | — | WO | disclosed |