Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR3 | P46089 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13704120 | 0.75 | GPR3 (0.60) | GPR3ALDH1A1GAAKDM4EDRD4 | |
| SCHEMBL22792110 | 0.75 | GPR3 (0.60) | GPR3ALDH1A1GAAKDM4EDRD4 | |
| SCHEMBL9377925 | 0.75 | GPR3 (1.00) | GPR3ALDH1A1GAAKDM4EPTPN2 | |
| SCHEMBL13704044 | 0.75 | GPR3 (0.60) | GPR3ALDH1A1GAAKDM4EDRD4 | |
| Formamide SCHEMBL28364111 | 0.68 | GPR3 (0.51) | GPR3ALDH1A1GAAKDM4EDRD4 | |
| SCHEMBL22622089 | 0.68 | ALDH1A1 (0.41) | GPR3ALDH1A1GAAKDM4EPTPN1 | |
| SCHEMBL10061676 | 0.67 | HTR5A (0.42) | GPR3PRCP | |
| SCHEMBL18433593 | 0.66 | GPR3 (0.34) | GPR3DRD2DRD4BRD4CCL2 | |
| SCHEMBL3099726 | 0.66 | GPR3 (0.62) | GPR3ALDH1A1GAAKDM4EDRD2 | |
| SCHEMBL13014907 | 0.64 | GPR3 (0.46) | GPR3PTPN2PTPN1SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127429-A1 | SOS1 INHIBITORS | Mirati Therapeutics, Inc. (US) | 2021-06-24 | — | — | WO | disclosed |