Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 12/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2358391 | 0.87 | FASN (0.53) | FASN | |
| SCHEMBL2355152 | 0.87 | FASN (0.42) | FASNHSP90AA1 | |
| SCHEMBL14151920 | 0.78 | FASN (0.68) | FASNHSP90AA1 | |
| SCHEMBL14346412 | 0.78 | FASN (0.68) | FASNHSP90AA1 | |
| SCHEMBL2355089 | 0.78 | FASN (0.40) | FASN | |
| SCHEMBL2357731 | 0.76 | FASN (0.44) | FASN | |
| SCHEMBL2356328 | 0.75 | FASN (0.66) | FASN | |
| SCHEMBL2357573 | 0.73 | FASN (0.81) | FASN | |
| SCHEMBL14152743 | 0.71 | FASN (0.63) | FASNHSP90AA1 | |
| SCHEMBL2299607 | 0.69 | FASN (0.81) | FASN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |