Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FASN | P49327 | 6/20 | 0.42 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 5/20 | 0.34 |
| ▸ | CCR2 | P41597 | 5/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.32 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2356332 | 0.87 | FASN (0.49) | FASNHSP90AA1 | |
| SCHEMBL2355089 | 0.85 | FASN (0.40) | FASN | |
| SCHEMBL2357335 | 0.85 | FASN (0.61) | FASN | |
| SCHEMBL2358391 | 0.83 | FASN (0.53) | FASN | |
| SCHEMBL2355763 | 0.82 | FASN (0.46) | FASN | |
| SCHEMBL14152133 | 0.77 | FASN (0.59) | FASNCCR1CCR2HSP90AA1 | |
| SCHEMBL14346404 | 0.77 | FASN (0.59) | FASNCCR1CCR2HSP90AA1 | |
| SCHEMBL2355150 | 0.74 | FASN (0.58) | FASN | |
| SCHEMBL2298684 | 0.73 | FASN (0.61) | FASNCCR1CCR2 | |
| SCHEMBL2298682 | 0.73 | FASN (0.61) | FASNCCR1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011103546-A1 | TRIAZOLONES AS FATTY ACID SYNTHASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2011-08-25 | — | — | WO | disclosed |